Casey Jessica T, Erickson Bradley A, Navai Neema, Zhao Lee C, Meeks Joshua J, Gonzalez Chris M
Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
J Urol. 2008 Jul;180(1):197-200. doi: 10.1016/j.juro.2008.03.056. Epub 2008 May 21.
There is limited literature examining urethral reconstruction in patients with neurogenic bladder dysfunction. We describe our experience of urethral reconstruction in men with concurrent neurogenic bladder.
A prospectively maintained database of all urethral reconstruction procedures performed by 1 surgeon was analyzed for patients with neurogenic bladder dysfunction. Patient characteristics including the etiology of neurogenic bladder, urethral pathology, urethral reconstructive technique, complications and recurrences were evaluated.
A total of 23 patients were included in the analysis. Urethral pathology included erosions (10), strictures (7), diverticula (3), urethrocutaneous fistulas (2), and a combination of diverticular and stricture disease (1). Median length of the urethral pathology was 5.0 cm (range 2.0 to 10.0). Overall urethral reconstruction was successful in 16 of 23 patients (69.6%) at a mean followup of 24.7 months (range 2 to 79). Success rates differed among the types of pathology with 60% for urethral erosions, 85.7% for urethral strictures, and 66.6% for urethral diverticula and fistulas. Of those cases of recurrence 4 of 7 (57%) were after urethral erosion repair. There was 1 (4.3%) postoperative complication and no patient underwent urinary diversion after recurrence.
When identified at an early stage, urethral reconstruction in patients with neurogenic bladder dysfunction offers acceptable outcomes with limited morbidity. Men undergoing reconstruction for urethral erosion had inferior outcomes compared to those with other urethral pathology.
关于神经源性膀胱功能障碍患者尿道重建的文献有限。我们描述了我们在患有神经源性膀胱的男性患者中进行尿道重建的经验。
对由1名外科医生进行的所有尿道重建手术的前瞻性维护数据库进行分析,纳入神经源性膀胱功能障碍患者。评估患者特征,包括神经源性膀胱的病因、尿道病理、尿道重建技术、并发症和复发情况。
共有23例患者纳入分析。尿道病理包括糜烂(10例)、狭窄(7例)、憩室(3例)、尿道皮肤瘘(2例)以及憩室和狭窄疾病合并存在(1例)。尿道病理的中位长度为5.0厘米(范围2.0至10.0厘米)。23例患者中有16例(69.6%)尿道重建总体成功,平均随访24.7个月(范围2至79个月)。不同病理类型的成功率有所不同,尿道糜烂为60%,尿道狭窄为85.7%,尿道憩室和瘘为66.6%。在复发的病例中,7例中有4例(57%)是在尿道糜烂修复后复发。术后有1例(4.3%)并发症,复发后无患者接受尿流改道。
神经源性膀胱功能障碍患者早期进行尿道重建可获得可接受的结果,并发症有限。与其他尿道病理患者相比,因尿道糜烂接受重建的男性患者预后较差。