Lipka Ulrike, Fuchs Rene, Lipka Volker
The Sainsbury Laboratory, John Innes Centre, Colney, Norwich NR4 7UH, UK.
Curr Opin Plant Biol. 2008 Aug;11(4):404-11. doi: 10.1016/j.pbi.2008.04.004. Epub 2008 May 20.
Immunity of an entire plant species against all genetic variants of a particular parasite is referred to as non-host resistance. Although non-host resistance represents the most common and durable form of plant resistance in nature, it has thus far been poorly understood at the molecular level. Recently, novel model systems have established the first mechanistic insights. The genetic dissection of Arabidopsis non-host resistance to non-adapted biotrophic powdery mildew fungi provided evidence for functionally redundant but operationally distinct pre- and post-invasion immune responses. Conceptually, these complex and successive defence mechanisms explain the durable and robust nature of non-host resistance. Pathogen lifestyle and infection biology, ecological parameters and the evolutionary relationship of the interaction partners determine differences and commonalities in other model systems.
整个植物物种对特定寄生虫的所有基因变体的免疫被称为非寄主抗性。尽管非寄主抗性是自然界中最常见且持久的植物抗性形式，但迄今为止，在分子水平上对其了解甚少。最近，新的模型系统提供了首批机制性见解。对拟南芥对非适应性活体营养型白粉菌的非寄主抗性进行的遗传剖析，为入侵前和入侵后功能冗余但操作不同的免疫反应提供了证据。从概念上讲，这些复杂且连续的防御机制解释了非寄主抗性持久且强大的本质。病原体的生活方式和感染生物学、生态参数以及相互作用伙伴的进化关系决定了其他模型系统中的差异和共性。
