Hernblad Tevell Elisabeth, Bergvall Kerstin, Egenvall Agneta
Bagarmossen Small Animal Hospital, Ljusnevagen 17, SE-128 48 Bagarmossen, Sweden.
Acta Vet Scand. 2008 May 25;50(1):11. doi: 10.1186/1751-0147-50-11.
Sebaceous adenitis (SA) is an uncommon, immune mediated skin disease in dogs. The aim was to retrospectively investigate SA in dogs in Sweden with respect to breed, sex and age distribution. A second aim was to retrospectively compare clinical signs in dogs with generalized SA and to estimate the survival after diagnosis in the English springer spaniel, standard poodle and the akita.
In total 34 Swedish veterinarians contributed with 104 clinically and histologically verified SA cases. Breed, gender and age at diagnosis were registered for each case. The degree of clinical signs at time for diagnosis and at follow-up and information about treatments, concurrent diseases and euthanasia were recorded for the springer spaniels, standard poodles and akitas using a standardized questionnaire.
A total of 104 cases of SA were included; most cases were recorded for the springer spaniel (n = 25), standard poodle (n = 21) and the akita (n = 10). These three breeds, together with the lhasa apso and the chow-chow, were the most common when national registry data from the Swedish Board of Agriculture and Swedish Kennel Club were considered. The mean age at diagnosis was 4.8 years. The proportion of males was 61%. When the springer spaniels, standard poodles and the akitas with generalized signs were compared (n = 51), the spaniels showed significantly more severe clinical signs than the poodles at diagnosis regarding alopecia, seborrhoea, pyoderma and the overall severity of clinical signs. At follow-up, the degree of clinical signs for otitis externa and pyoderma differed significantly between the breeds. The estimated median survival time was 42 months. In dogs where data regarding survival was available at the end of the study (n = 44), SA was reported to be the reason for euthanasia in 14 dogs, whereof 7 within 24 months after diagnosis.
The result of this study implicates that the English springer spaniel is a breed predisposed to SA and that it has more severe clinical signs than the standard poodle. A large proportion of the dogs (spaniel, poodle and akita) investigated regarding survival were reported to have been euthanized to great extent due to the disease.
皮脂腺炎（SA）是一种在犬类中不常见的免疫介导性皮肤病。目的是回顾性调查瑞典犬类中SA的品种、性别和年龄分布情况。第二个目的是回顾性比较全身性SA犬的临床症状，并估计英国激飞猎犬、标准贵宾犬和秋田犬确诊后的生存期。
共有34名瑞典兽医提供了104例经临床和组织学确诊的SA病例。记录每个病例的品种、性别和确诊年龄。使用标准化问卷记录激飞猎犬、标准贵宾犬和秋田犬确诊时和随访时的临床症状程度以及治疗、并发疾病和安乐死的信息。
共纳入104例SA病例；大多数病例记录于激飞猎犬（n = 25）、标准贵宾犬（n = 21）和秋田犬（n = 10）。当考虑瑞典农业委员会和瑞典养犬俱乐部的国家登记数据时，这三个品种以及拉萨犬和松狮犬是最常见的。确诊时的平均年龄为4.8岁。雄性比例为61%。比较有全身性症状的激飞猎犬、标准贵宾犬和秋田犬（n = 51）时，在诊断时，就脱毛、皮脂溢、脓皮病和临床症状的总体严重程度而言，激飞猎犬的临床症状比贵宾犬明显更严重。随访时，各品种外耳道炎和脓皮病的临床症状程度有显著差异。估计中位生存期为42个月。在研究结束时可获得生存数据的犬只（n = 44）中，有14只犬因SA被报告实施安乐死，其中7只在确诊后24个月内。
本研究结果表明，英国激飞猎犬是易患SA的品种，且其临床症状比标准贵宾犬更严重。在调查生存期的犬只（激飞猎犬、贵宾犬和秋田犬）中，很大一部分据报告因该病在很大程度上被实施安乐死。
