Reichler I M, Hauser B, Schiller I, Dunstan R W, Credille K M, Binder H, Glaus T, Arnold S
Department of Reproduction, University of Zurich, Switzerland.
Vet Dermatol. 2001 Oct;12(5):243-53. doi: 10.1046/j.0959-4493.2001.00251.x.
Ninety-seven pure-bred Akitas were examined clinically and histologically for sebaceous adenitis. The diagnosis was established histologically in 23 Akitas by demonstrating an inflammatory reaction targeted against the sebaceous glands or a reduction in the number of glands. The clinical course of sebaceous adenitis in the Akita was similar to that seen in other breeds. The first skin lesions occurred mainly on the dorsal midline and ears. Compared with the Poodle, the age at first onset of the disease was more variable and the hair loss affected mainly the undercoat. The progression of sebaceous gland destruction varied between dogs and was not seen in all cases. Because bud-like sebaceous gland proliferation could be identified, it seems that regeneration of the sebaceous glands may occur. An autosomal recessive inheritance appears to be possible. Apart from a genetic background, immune-mediated factors possibly influence the onset and course of sebaceous adenitis.
对97只纯种秋田犬进行了皮脂腺炎的临床和组织学检查。通过显示针对皮脂腺的炎症反应或腺体数量减少，在23只秋田犬中通过组织学确诊。秋田犬皮脂腺炎的临床病程与其他品种相似。最初的皮肤病变主要发生在背部中线和耳朵。与贵宾犬相比，该病首次发病的年龄更具变异性，脱毛主要影响底层绒毛。皮脂腺破坏的进展在不同犬只之间有所不同，并非在所有病例中都能观察到。由于可以识别出芽状皮脂腺增生，似乎皮脂腺可能会发生再生。可能存在常染色体隐性遗传。除了遗传背景外，免疫介导因素可能影响皮脂腺炎的发病和病程。
