Aswani J, Thandar M, Otiti J, Fagan J
Division of Otolaryngology, Faculty of Health Sciences, University of Cape Town, South Africa.
J Laryngol Otol. 2009 Mar;123(3):333-8. doi: 10.1017/S0022215108002557. Epub 2008 May 23.
To determine whether, in a developing world context, early oral feeding after laryngectomy is safe, cost-effective and appropriate.
A prospective study of early oral feeding after laryngectomy, compared with retrospective, historical delayed feeding controls.
Forty patients underwent total laryngectomy for advanced carcinoma of the larynx with or without hypopharyngeal involvement, not requiring tongue base resection or myocutaneous flaps, and were commenced on oral feeding on the second post-operative day. Thirty-nine laryngectomy patients previously managed in the same unit who had received conventional, delayed oral feeding served as controls.
Pharyngocutaneous fistulae developed in 20 per cent of the early feeding patients, compared with 15.4 per cent of the delayed oral feeding controls (p = 0.592). For patients who did not develop fistulae, hospitalisation was shorter in the early oral feeding group (p = 0.007).
Early oral feeding for laryngectomy patients is recommended, both in developed and developing countries.
确定在发展中国家背景下,喉切除术后早期经口进食是否安全、具有成本效益且合适。
一项关于喉切除术后早期经口进食的前瞻性研究,与回顾性、历史性延迟进食对照组进行比较。
40例因晚期喉癌行全喉切除术的患者,伴有或不伴有下咽受累,无需舌根切除或肌皮瓣,术后第二天开始经口进食。39例此前在同一科室接受传统延迟经口进食的喉切除患者作为对照。
早期进食患者中20%发生咽皮肤瘘,延迟经口进食对照组为15.4%(p = 0.592)。对于未发生瘘的患者,早期经口进食组住院时间较短(p = 0.007)。
无论是在发达国家还是发展中国家,均建议对喉切除患者进行早期经口进食。