Duffy Austin, Shia Jinru, Huitzil-Melendez Fidel David, Fong Yuman, O'Reilly Eileen M
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Clin Colorectal Cancer. 2008 Mar;7(2):140-3. doi: 10.3816/CCC.2008.n.019.
A 32-year-old Asian male presented with perforated sigmoid colorectal cancer (CRC) and large, unresectable hepatic metastasis. After surgery for his primary tumor, he received 6 months of FOLFOX (5-fluorouracil/leucovorin/ oxaliplatin) plus bevacizumab and achieved a partial response. He underwent hepatic metastasectomy and was found to have had a complete pathologic response (pCR) to treatment. The literature regarding pCR with chemotherapy in CRC and the implications for further management is discussed herein.
一名32岁的亚洲男性因乙状结肠直肠癌（CRC）穿孔并伴有无法切除的巨大肝转移而就诊。在对其原发性肿瘤进行手术后，他接受了6个月的FOLFOX（5-氟尿嘧啶/亚叶酸钙/奥沙利铂）加贝伐单抗治疗，并获得了部分缓解。他接受了肝转移瘤切除术，结果发现对治疗有完全病理缓解（pCR）。本文讨论了关于CRC化疗后pCR及其对进一步治疗意义的文献。
