Musial Frauke, Häuser Winfried, Langhorst Jost, Dobos Gustav, Enck Paul
Complementary and Integrative Medicine, University of Duisburg-Essen, Department of Internal Medicine, Kliniken Essen-Mitte, Germany.
J Psychosom Res. 2008 Jun;64(6):589-97. doi: 10.1016/j.jpsychores.2008.02.024. Epub 2008 Apr 28.
The psychophysiology of visceral pain as it relates to gastrointestinal motility, visceral sensitivity, and putative mechanisms of the processing of visceral stimuli by the central and peripheral nervous systems are discussed. Peripheral mechanisms may include low-grade mucosal inflammation, and it is likely that central nervous mechanisms such as neuronal plasticity at the level of the spinal cord and attentional bias at the cortical level are relevant for the chronification of visceral pain. From a psychophysiological perspective, visceral pain therefore remains a complex symptom because behavioral variables, such as the way an individual deals with stress, may be as important for the etiology of visceral pain as, for example, a history of inflammation.
本文讨论了内脏痛的心理生理学，涉及胃肠动力、内脏敏感性以及中枢和外周神经系统处理内脏刺激的假定机制。外周机制可能包括低度黏膜炎症，而诸如脊髓水平的神经元可塑性和皮质水平的注意力偏差等中枢神经机制可能与内脏痛的慢性化有关。从心理生理学角度来看，内脏痛仍然是一种复杂的症状，因为行为变量，比如个体应对压力的方式，对于内脏痛的病因可能与炎症史同等重要。
