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Aliment Pharmacol Ther. 2019 Jul;50(2):132-143. doi: 10.1111/apt.15325. Epub 2019 Jun 3.
2
The Increased Level of Depression and Anxiety in Irritable Bowel Syndrome Patients Compared with Healthy Controls: Systematic Review and Meta-analysis.肠易激综合征患者与健康对照相比抑郁和焦虑水平升高：系统评价与荟萃分析
J Neurogastroenterol Motil. 2017 Jul 30;23(3):349-362. doi: 10.5056/jnm16220.
3
Risk for Irritable Bowel Syndrome in Fibromyalgia Patients: A National Database Study.纤维肌痛患者患肠易激综合征的风险：一项全国性数据库研究。
Medicine (Baltimore). 2017 Apr;96(14):e6657. doi: 10.1097/MD.0000000000006657.
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Irritable Bowel Syndrome and Stress-Related Psychiatric Co-morbidities: Focus on Early Life Stress.肠易激综合征与应激相关精神共病：关注早期生活应激
Handb Exp Pharmacol. 2017;239:219-246. doi: 10.1007/164_2016_128.
5
Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis.肠易激综合征（IBS）中的焦虑和抑郁共病：一项系统评价和荟萃分析。
Eur Arch Psychiatry Clin Neurosci. 2014 Dec;264(8):651-60. doi: 10.1007/s00406-014-0502-z. Epub 2014 Apr 6.
6
Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis.全球肠易激综合征的患病率和危险因素：一项荟萃分析。
Clin Gastroenterol Hepatol. 2012 Jul;10(7):712-721.e4. doi: 10.1016/j.cgh.2012.02.029. Epub 2012 Mar 15.
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Irritable bowel syndrome is strongly associated with generalized anxiety disorder: a community study.肠易激综合征与广泛性焦虑障碍密切相关：一项社区研究。
Aliment Pharmacol Ther. 2009 Sep 15;30(6):643-51. doi: 10.1111/j.1365-2036.2009.04074.x. Epub 2009 Jun 23.
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Psychophysiology of visceral pain in IBS and health.肠易激综合征和健康状态下内脏痛的心理生理学
J Psychosom Res. 2008 Jun;64(6):589-97. doi: 10.1016/j.jpsychores.2008.02.024. Epub 2008 Apr 28.
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生活质量和肠易激综合征患者心理测量评估：一项观察性队列研究。

Quality of life and psychometric evaluation of patients diagnosed with irritable bowel syndrome: an observational cohort study.

机构信息

MD. General Surgeon, Department of General Surgery, Yenimahalle Training and Research Hospital, Yildirim Beyazıt University, Ankara, Turkey.

MD. Psychiatrist, Private Emre Kizil Psychiatry Clinic, Cankaya, Ankara, Turkey.

出版信息

Sao Paulo Med J. 2020 Jul-Aug;138(4):282-286. doi: 10.1590/1516-3180.2019.0527.R1.16042020.

DOI:10.1590/1516-3180.2019.0527.R1.16042020
PMID:32556060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9673838/
Abstract

BACKGROUND

Very few data are available for evaluating health-related quality of life among people with irritable bowel syndrome (IBS) and even fewer data are available in relation to anxiety and depression status among these patients.

OBJECTIVES

To evaluate the quality of life, anxiety and depression status of patients with IBS.

DESIGN AND SETTING

Observational cohort study conducted in a tertiary-care university hospital.

METHODS

Patients who had recently been diagnosed with IBS and who had been followed up for IBS-specific treatment for at least three months were included. A quality of life (QoL) survey, the Beck Anxiety Index (BAI) and the Hamilton Depression Index (HAM-D) were applied to the patients.

RESULTS

In total, 274 patients with IBS were included in the study cohort. These patients presented very high baseline scores for anxiety and depression, and very poor QoL results.

CONCLUSION

Our study showed that IBS had a very high impact on these patients, regarding their anxiety and depression levels, alongside very poor results relating to quality of life.

摘要

背景

评估肠易激综合征（IBS）患者的健康相关生活质量的数据非常有限，而这些患者的焦虑和抑郁状况的数据则更为有限。

目的

评估 IBS 患者的生活质量、焦虑和抑郁状况。

设计和设置

在一家三级保健大学医院进行的观察性队列研究。

方法

纳入最近被诊断为 IBS 并接受至少三个月 IBS 特异性治疗的患者。对患者进行生活质量（QoL）调查、贝克焦虑指数（BAI）和汉密尔顿抑郁指数（HAM-D）评估。

结果

共有 274 名 IBS 患者纳入研究队列。这些患者的焦虑和抑郁基线评分非常高，生活质量结果非常差。

结论

我们的研究表明，IBS 对这些患者的焦虑和抑郁水平有很大的影响，同时生活质量也很差。