60赫兹磁场在自然条件下对陆地蜗牛（野蛞蝓）阿片类药物诱导的“镇痛”的抑制作用。

Inhibitory effects of 60-Hz magnetic fields on opiate-induced "analgesia" in the land snail, Cepaea nemoralis, under natural conditions.

作者信息

Tysdale D M, Lipa S M, Ossenkopp K P, Kavaliers M

机构信息

Division of Oral Biology, Faculty of Dentistry, University of Western Ontario, London, Canada.

出版信息

Physiol Behav. 1991 Jan;49(1):53-6. doi: 10.1016/0031-9384(91)90229-h.

DOI:10.1016/0031-9384(91)90229-h

PMID:1850141

Abstract

There is accumulating laboratory evidence that magnetic fields can affect a variety of opioid-mediated behavioral and physiological functions in both vertebrates and invertebrates. The present study examined the effects of various durations (0.50, 1.0 and 2.0 h) of exposure to a low intensity (1.0 gauss rms) 60-Hz magnetic field on opioid-mediated aversive thermal ("nociceptive") responses and morphine-induced "analgesia" in the land snail, Cepaea nemoralis, under natural environmental conditions. Exposure to the powerline-related 60-Hz magnetic fields significantly attenuated morphine-induced analgesia and the basal nociceptive responses of Cepaea, with the degree of attenuation being related to the duration of exposure to the magnetic fields. These results with Cepaea show that 60-Hz magnetic fields can affect opioid-mediated behavioral responses outside the laboratory under natural environmental conditions.

摘要

越来越多的实验室证据表明，磁场能够影响脊椎动物和无脊椎动物中多种由阿片类物质介导的行为和生理功能。本研究在自然环境条件下，检测了陆地蜗牛（黄蛞蝓）暴露于低强度（均方根值1.0高斯）60赫兹磁场不同时长（0.50、1.0和2.0小时）对阿片类物质介导的厌恶性热（“伤害性”）反应以及吗啡诱导的“镇痛”的影响。暴露于与输电线相关的60赫兹磁场显著减弱了吗啡诱导的镇痛作用以及黄蛞蝓的基础伤害性反应，减弱程度与暴露于磁场的时长有关。黄蛞蝓的这些结果表明，在自然环境条件下，60赫兹磁场能够在实验室之外影响由阿片类物质介导的行为反应。