The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology.
作者信息
Krajewski Megan L, Hsu Lewis L, Gladwin Mark T
出版信息
Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H4-7. doi: 10.1152/ajpheart.00499.2008. Epub 2008 May 23.
Abstract
摘要
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The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology.是先有鸡还是先有蛋？剖析游离血红蛋白与活性氧在镰状细胞病理生理学中的作用。
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本文引用的文献
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Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.转基因敲除镰状小鼠的精氨酸治疗通过减少非一氧化氮血管舒张剂、溶血和氧化应激来改善微血管功能。
Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H39-47. doi: 10.1152/ajpheart.00162.2008. Epub 2008 May 2.
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