Stoeff S, Jovtchev Sv, Dikov I, Kolarov D, Galabova T, Trifonova N, Hadjieva Sv, Mladenova A, Lambreva L, Penev M
Department of Physics and Biophysics, Medical Faculty, Medical University Sofia, Sofia, Bulgaria.
Clin Hemorheol Microcirc. 2008;39(1-4):381-4.
Accepted methods of the ESR methodology (the Westergren mode and ZSR mode) and its alternative the plasma viscosity were tested for diagnostic utility in pregnancy induced hypertension and pre-eclampsia. The receiver-operating characteristic curve (ROC) analysis approved moderate diagnostic accuracy for the ESR methodology and supplied support for its preliminary estimated cutoff values but failed to indicate cogent discernment of pathology by values of plasma viscosity. Likely pathological whole blood alterations boost the erythrocyte aggregation while the concomitant depletion of macromolecules degrades plasma viscosity values.
对红细胞沉降率（ESR）方法的公认模式（魏氏法和ZSR法）及其替代方法血浆粘度进行了测试，以评估其在妊娠高血压和先兆子痫诊断中的效用。受试者工作特征曲线（ROC）分析证实ESR方法具有中等诊断准确性，并支持其初步估计的临界值，但未能表明血浆粘度值对病理情况有明确的鉴别能力。可能的病理性全血改变会增强红细胞聚集，而同时大分子物质的减少会降低血浆粘度值。
