Wallet Frédéric, Labalette Pierre, Herwegh Stéphanie, Loiez Caroline, Margaron Fabrice, Courcol René J
Pole de Microbiologie, Laboratoire de Bacteriologie-Hygiene, Lille Cedex, France.
Jpn J Infect Dis. 2008 May;61(3):214-5.
The present paper describes a case of bilateral panuveitis due to Borrelia burgdorferi sensu lato diagnosed by a PCR approach using cerebral spinal fluid. Since the culture of B. burgdorferi takes a long time to grow and the accuracy of serological tests is doubtful in patients, the PCR method of amplifying a B. burgdorferi flagellin could be suitable to make a positive diagnosis in a case of atypical clinical history of Lyme disease.
本文描述了一例通过使用脑脊液的聚合酶链反应(PCR)方法诊断出的由伯氏疏螺旋体复合群引起的双侧全葡萄膜炎病例。由于伯氏疏螺旋体的培养生长需要很长时间,并且血清学检测在患者中的准确性存疑,因此扩增伯氏疏螺旋体鞭毛蛋白的PCR方法可能适用于对莱姆病非典型临床病史的病例做出阳性诊断。