Yu Sen-Hai, Wang Hu, Wu Xian-Hong, Ma Xiao, Liu Pei-Yun, Liu Yu-Fang, Zhao Yan-Mei, Morishima Yasuyuki, Kawanaka Masanori
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China.
Jpn J Infect Dis. 2008 May;61(3):242-6.
An epidemiological investigation on echinococcosis was made in Jiuzhi County of Qinghai Province, western China. Ultrasonography and an indirect hemagglutination test revealed a morbidity of 8.0% (124/1,549) and a seroprevalence of 25.8% (287/1,113), respectively, in the Tibetan population. The morbidity in herdsmen (16.6%) and Buddhist priests (15%) was significantly higher than that in other occupation groups (3.2%), and it was higher in females (9.8%) than in males (6.2%). The ultrasound images showed a coexistence of cystic echinococcosis (CE) and alveolar echinococcosis (AE), occupying 69 and 31% of the cases, respectively. An Echinococcus Western blot assay was performed as a serological backup test for differentiating CE and AE. The assay revealed that serum samples from most cases with a positive AE image showed a specific antibody against antigen bands at 16/18 kDa. Autopsy proved that 9 out of 12 stray dogs were infected with Echinococcus granulosus (n = 8) and E. multilocularis (n = 1). Inspection at the abattoirs demonstrated a hydatid rate of 78.5% in yaks and 82.6% in sheep. The data indicate that Jiuzhi County is an important endemic area for both CE and AE, in both human and animal populations.
在中国西部青海省久治县开展了一项关于包虫病的流行病学调查。超声检查和间接血凝试验结果显示，藏族人群中包虫病发病率为8.0%（124/1549），血清阳性率为25.8%（287/1113）。牧民（16.6%）和喇嘛（15%）的发病率显著高于其他职业人群（3.2%），女性发病率（9.8%）高于男性（6.2%）。超声图像显示，囊性包虫病（CE）和泡型包虫病（AE）并存，分别占病例的69%和31%。采用棘球蚴蛋白免疫印迹法作为区分CE和AE的血清学辅助检测方法。该检测显示，大多数AE图像阳性病例的血清样本显示出针对16/18 kDa抗原条带的特异性抗体。尸检证明，12只流浪狗中有9只感染了细粒棘球绦虫（8只）和多房棘球绦虫（1只）。屠宰场检查表明，牦牛的包虫感染率为78.5%，绵羊为82.6%。这些数据表明，久治县是人和动物群体中CE和AE的重要流行区。
