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一种具有紧致功效的新型植物提取物复合配方的局部制剂。一项双盲试验中的临床和非侵入性评估。

Topical formulation of a new plant extract complex with refirming properties. Clinical and non-invasive evaluation in a double-blind trial.

机构信息

Department of Dermatology, IRCCS Policlinico S. Matteo, Università di Pavia, 27100 Pavia, Italy.

出版信息

Int J Cosmet Sci. 2000 Jun;22(3):201-6. doi: 10.1046/j.1467-2494.2000.00045.x.

Abstract

We tested an OTC formulation versus placebo in a double-blind trial to evaluate its ability to improve elasticity and firmness of the skin. The clinical non-invasive evaluation in 20 volunteers shows: 1. No adverse reactions such as itching or irritation 2. Efficacy and cosmetic acceptibility of the test cream 3. An increase in electrical capacitance (moisture content) even though without statistical significance. This result is not surprising because the patients had healthy skin and were relatively young (aged 20-25) 4. A very significant improvement in the biomechanical properties (extensibility and firmness) of the skin. This increase was statistically significant (P < 0.02) The main components of the cream (boswellic acids, Sylibin and Centella asiatica extracts) were formulated as complexes with lyso-phospholipids and soya bean non-saponifiable lipids.

摘要

我们在一项双盲试验中测试了一种非处方制剂与安慰剂相比,以评估其改善皮肤弹性和紧致度的能力。对 20 名志愿者的临床无创评估显示:1. 无瘙痒或刺激等不良反应;2. 试验乳膏的功效和美容可接受性;3. 电容量(含水量)增加,尽管无统计学意义。这一结果并不奇怪,因为这些患者皮肤健康,相对年轻(20-25 岁);4. 皮肤生物力学特性(伸展性和紧致度)有非常显著的改善。这种增加具有统计学意义(P<0.02)。乳膏的主要成分(乳香酸、西利宾和积雪草提取物)被制成与溶磷脂和大豆不可皂化物脂质的复合物。

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