Veien Niels K, Hattel Thais, Laurberg Grete
The Dermatology Clinic, Vesterbro 99, DK-9000 Aalborg, Denmark.
Contact Dermatitis. 2008 Jun;58(6):335-9. doi: 10.1111/j.1600-0536.2008.01346.x.
Hand eczema is a common dermatosis, often with a chronic course.
To follow a well-described cohort of patients with hand eczema for 5 years.
522 consecutive hand eczema patients (175 men and 347 women) seen in a private practice of dermatology were sent a questionnaire once a year for 5 years.
After 1 year, the response rate was 80% (417 of 522), and after 5 years, the rate was 68%. After 1 year, 81% of the 417 respondents reported that they still had persistent or intermittent hand eczema. After 5 years, this number was 65% (232 of 355). The larger the area involved at the initial examination, the poorer the prognosis. After 1 year, 48% of the patients felt that their hand eczema had improved, while 6.7% felt that it had worsened. 25% of those who responded stated that they never used gloves. Few patients could provide new information about the cause of the dermatitis during the 5-year follow-up.
Hand eczema is a chronic dermatosis. Although treatment may improve hand eczema, it rarely clears completely. Evidence-based measures need to be developed for the long-term management of hand eczema.
手部湿疹是一种常见的皮肤病，病程通常较长。
对一组详细描述的手部湿疹患者进行为期5年的随访。
在一家皮肤科私人诊所就诊的522例连续性手部湿疹患者（175例男性和347例女性），在5年时间里每年收到一份调查问卷。
1年后，应答率为80%（522例中的417例），5年后，应答率为68%。1年后，417例应答者中有81%报告他们仍有持续性或间歇性手部湿疹。5年后，这一数字为65%（355例中的232例）。初次检查时受累面积越大，预后越差。1年后，48%的患者感觉他们的手部湿疹有所改善，而6.7%的患者感觉病情加重。25%的应答者表示他们从未使用过手套。在5年的随访期间，很少有患者能提供有关皮炎病因的新信息。
手部湿疹是一种慢性皮肤病。尽管治疗可能改善手部湿疹，但很少能完全治愈。需要制定基于证据的措施用于手部湿疹的长期管理。
