Veien Niels K, Hattel Thais, Laurberg Grete
The Dermatology Clinic, Vesterbro 99, DK-9000 Aalborg, Denmark.
Contact Dermatitis. 2008 Jun;58(6):330-4. doi: 10.1111/j.1600-0536.2008.01345.x.
Hand eczema is a common dermatosis. The course is often protracted. The prognosis is not well described.
To describe in detail a consecutive cohort of hand eczema patients with regard to aetiology and morphology as well as the dynamics of the hand eczema.
This prospective study included 522 consecutive patients (175 men and 347 women with hand eczema) seen in 1 year in a private practice of dermatology. 425 (81%) of the patients were patch tested in relation to the current study. Most of the remainder had been previously patch tested.
38% had mild dermatitis, 49% had dermatitis of moderate severity, and 11% had severe dermatitis. 23% had had dermatitis for more than 10 years. 33% had irritant contact dermatitis, 13% of the men and 20% of the women had allergic contact dermatitis, and 15% of the men and 16% of the women had atopic dermatitis. For 34% of the men and 29% of the women, the dermatitis was certainly or possibly occupational. There was no relationship to smoking.
The majority of this cohort of hand eczema patients had long-standing disease. Irritant contact dermatitis was the most common aetiological diagnosis.
手部湿疹是一种常见的皮肤病。病程往往迁延不愈。预后情况尚无详尽描述。
详细描述一组连续性手部湿疹患者的病因、形态以及手部湿疹的动态变化情况。
这项前瞻性研究纳入了在一家皮肤科私人诊所1年内连续就诊的522例患者（175例男性和347例女性手部湿疹患者）。在本研究中，425例（81%）患者进行了斑贴试验。其余大多数患者之前已进行过斑贴试验。
38%为轻度皮炎，49%为中度皮炎，11%为重度皮炎。23%的患者患皮炎超过10年。33%为刺激性接触性皮炎，13%的男性和20%的女性为过敏性接触性皮炎，15%的男性和16%的女性为特应性皮炎。34%的男性和29%的女性的皮炎肯定或可能与职业有关。与吸烟无关。
该组手部湿疹患者大多数患有长期疾病。刺激性接触性皮炎是最常见的病因诊断。
