Sorensen Janice, Kondrup Jens, Prokopowicz Jacek, Schiesser Marc, Krähenbühl Lukas, Meier Rémy, Liberda Martin
Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, 30 Rolighedsvej, 1958 Frederiksberg C, Denmark.
Clin Nutr. 2008 Jun;27(3):340-9. doi: 10.1016/j.clnu.2008.03.012. Epub 2008 May 27.
BACKGROUND & AIMS: The aim of the study was to implement nutritional risk screening (NRS-2002) and to assess the association between nutritional risk and clinical outcome.
NRS-2002 was implemented in 26 hospital departments (surgery, internal medicine, oncology, intensive care, gastroenterology and geriatrics) in Austria, the Czech Republic, Egypt, Germany, Hungary, Lebanon, Libya, Poland, Romania, Slovakia, Spain and Switzerland. Being a prospective cohort study, randomly selected adult patients were included at admission and followed during their hospitalisation. Data were collected on the nutritional risk screening, complications, mortality, length of stay and discharge. The correlation between risk status and clinical outcome was assessed and adjusted for confounders (age, speciality, diagnoses, comorbidity, surgery, cancer and region) by multivariate regression analysis.
Of the 5051 study patients, 32.6% were defined as 'at-risk' by NRS-2002. 'At-risk' patients had more complications, higher mortality and longer lengths of stay than 'not at-risk' patients and these variables were significantly related to components of NRS-2002, also when adjusted for confounders.
Components of NRS-2002 are independent predictors of poor clinical outcome.
本研究旨在实施营养风险筛查（NRS - 2002）并评估营养风险与临床结局之间的关联。
在奥地利、捷克共和国、埃及、德国、匈牙利、黎巴嫩、利比亚、波兰、罗马尼亚、斯洛伐克、西班牙和瑞士的26个医院科室（外科、内科、肿瘤科、重症监护室、胃肠病科和老年病科）实施NRS - 2002。作为一项前瞻性队列研究，随机选取成年患者在入院时纳入研究，并在其住院期间进行随访。收集有关营养风险筛查、并发症、死亡率、住院时间和出院情况的数据。通过多变量回归分析评估风险状态与临床结局之间的相关性，并对混杂因素（年龄、专业、诊断、合并症、手术、癌症和地区）进行校正。
在5051例研究患者中，32.6%被NRS - 2002定义为“有风险”。“有风险”的患者比“无风险”的患者有更多并发症、更高的死亡率和更长的住院时间，并且在对混杂因素进行校正后，这些变量与NRS - 2002的组成部分显著相关。
NRS - 2002的组成部分是临床结局不良的独立预测因素。
