Beck Gabriele M, De Becker Jan, Jones Alun C, von Falkenhausen Marcus, Willinek Winfried A, Gieseke Jürgen
Philips Medical Systems, Best, Netherlands.
J Magn Reson Imaging. 2008 Jun;27(6):1461-7. doi: 10.1002/jmri.21393.
To investigate a new image acquisition method that enables an accurate hepatic arterial phase definition and the visualization of contrast agent uptake processes in abdominal organs like liver, spleen, and pancreas.
A 3D turbo gradient echo method where a fat suppression prepulse is followed by the acquisition of several profiles was combined with an elliptical centric k-space ordering technique and 3D dynamic elliptical centric keyhole. The new k-space ordering method (CENTRA+) was validated experimentally. In an initial clinical evaluation phase the method was employed in five patients to assess the accuracy of the hepatic arterial phase definition and the visualization of the contrast uptake processes in dynamic scanning in abdominal organs like liver, spleen, and pancreas.
In total, five patients were evaluated using the new k-space order. Our initial results indicate that the new k-space order allows consistent capture of the hepatic arterial phase. In dynamic scanning the extreme short temporal resolution obtained with 3D elliptical centric keyhole enables contrast enhancement to be followed in organs with fast contrast uptake characteristics.
The elliptical centric nature of the new image acquisition method effectively allows capture of the contrast enhancement processes with good fat suppression.
研究一种新的图像采集方法，该方法能够准确界定肝动脉期，并可视化肝脏、脾脏和胰腺等腹部器官中造影剂的摄取过程。
一种三维快速梯度回波方法，在脂肪抑制预脉冲之后采集多个层面像，并结合椭圆中心k空间排序技术和三维动态椭圆中心钥匙孔技术。新的k空间排序方法（CENTRA+）经过了实验验证。在初始临床评估阶段，该方法应用于5例患者，以评估肝动脉期界定的准确性以及肝脏、脾脏和胰腺等腹部器官动态扫描中造影剂摄取过程的可视化情况。
总共对5例患者采用新的k空间排序进行了评估。我们的初步结果表明，新的k空间排序能够一致地捕捉肝动脉期。在动态扫描中，三维椭圆中心钥匙孔技术获得的极短时间分辨率能够跟踪具有快速造影剂摄取特征的器官中的造影剂增强情况。
新图像采集方法的椭圆中心特性能够有效地捕捉造影剂增强过程，并具有良好的脂肪抑制效果。
