Betalli Pietro, De Corti Federica, Minucci Daria, Mazzarotto Renzo, Meneghini Luisa, Bisogno Gianni, Cecchetto Giovanni
Pediatric Surgery Unit, Department of Pediatrics, University Hospital, Padova, Italy.
Pediatr Blood Cancer. 2008 Oct;51(4):550-2. doi: 10.1002/pbc.21641.
Vaginal strictures are rare entities in pediatric population, mainly due to congenital genito-urinary tract malformations and sequelae of their surgical treatment, recurrent vaginitis and multisciplinary therapy for malignant tumors. The therapy of choice is not standardized. Conservative treatments are favored and dilators seem to be very effective, but their use in children is difficult due to poor compliance. We report our experience with topical application of mitomycin-C in a female with vaginal stricture secondary to brachytherapy.
阴道狭窄在儿科人群中较为罕见，主要归因于先天性泌尿生殖道畸形及其手术治疗的后遗症、复发性阴道炎以及恶性肿瘤的多学科治疗。治疗方法尚无标准化。保守治疗更受青睐，扩张器似乎非常有效，但由于依从性差，在儿童中使用困难。我们报告了局部应用丝裂霉素-C治疗一名因近距离放疗继发阴道狭窄女性患者的经验。
