Karaca Esra, Hockenberger Asli S
Department of Textile Engineering, Faculty of Engineering and Architecture, Uludag University, Bursa, Turkey.
J Biomed Mater Res B Appl Biomater. 2008 Nov;87(2):580-9. doi: 10.1002/jbm.b.31136.
This study has analyzed fracture morphology of four nonabsorbable commercially available sutures before and after implantation in rats. Also, tensile and knot strength retention have been evaluated after 3 and 8 weeks in vivo. Scanning electron and optical light microscopes were used for analysis of fracture morphologies and surface changes of the sutures. A clear effect of in vivo on the tensile and knot strength changes, and the fracture mechanism was seen for braided sutures. The suture size was also important for braided sutures, as fibrous tissue formation plays an important role in terms of the size. The fiber's surface properties were also important for the fracture morphology. A smooth and even surface was not suitable for the fibrous tissue formation as seen in monofilament sutures. Therefore, the polymer type was very important for the monofilament sutures, as it was the most important parameter to determine the fracture morphology and was not affected by the implantation and the implantation time. The size of the suture was also important for the polypropylene in terms of axial splitting before and after implantation. This, however, was not the case for knot strength tests. The knot was undone regardless of the size. Surface characteristics were very important for braided sutures, as they have a rough surface that supports tissue formation on the fracture mechanism, tensile and knot strength. Silk suture has single filaments with no regular diameter and smooth surface. Therefore, silk suture has more tissue formation postimplantation compared to polyester suture.
本研究分析了四种市售不可吸收缝线在植入大鼠体内前后的断裂形态。此外，还评估了体内3周和8周后的拉伸强度和结强度保留情况。使用扫描电子显微镜和光学显微镜分析缝线的断裂形态和表面变化。对于编织缝线，观察到体内对拉伸强度和结强度变化以及断裂机制有明显影响。缝线尺寸对编织缝线也很重要，因为纤维组织形成在尺寸方面起着重要作用。纤维的表面特性对断裂形态也很重要。如单丝缝线所示，光滑均匀的表面不适合纤维组织形成。因此，聚合物类型对单丝缝线非常重要，因为它是决定断裂形态的最重要参数，且不受植入和植入时间的影响。缝线尺寸对聚丙烯缝线在植入前后的轴向分裂方面也很重要。然而，在结强度测试中情况并非如此。无论尺寸如何，结都会松开。表面特性对编织缝线非常重要，因为它们具有粗糙的表面，在断裂机制、拉伸强度和结强度方面支持组织形成。丝线缝线具有直径不规则且表面光滑的单丝。因此，与聚酯缝线相比，丝线缝线在植入后有更多的组织形成。
