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[Malignant fibrous histiocytoma of soft tissue: description of 10 cases].

作者信息

Povar J, Franco J M, Muñoz J R, Horndler C, Arazo P, Portoles A, Velilla J, Gutiérrez A

机构信息

Departamento de Medicina Interna, Hospital Miguel Servet, Zaragoza.

出版信息

Med Clin (Barc). 1991 Jan 12;96(1):6-10.

PMID:1850813
Abstract

We analyze the clinical and histological features of 10 cases of malignant fibrous histiocytoma of soft tissue. Nine belonged to the pleomorphic-verticillate variety and one was myxoid. The initial clinical feature was a palpable mass in all cases except three with retroperitoneal localization, where constitutional symptoms predominated. After therapy (surgery in all, associated with radiotherapy in four), seven patients had local relapse and two had distant metastases. 50% died, with a mean survival of 13 months. We discuss the prognostic factors and the therapeutic approach, with emphasis on aggressive therapy and the need for radical surgery and postoperative adjuvant therapy.

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