果蝇中通过一个新基因的起源而产生的求偶行为的进化。
The evolution of courtship behaviors through the origination of a new gene in Drosophila.
作者信息
Dai Hongzheng, Chen Ying, Chen Sidi, Mao Qiyan, Kennedy David, Landback Patrick, Eyre-Walker Adam, Du Wei, Long Manyuan
机构信息
Committee on Genetics, University of Chicago, 920 East 58th Street, Chicago, IL 60637, USA.
出版信息
Proc Natl Acad Sci U S A. 2008 May 27;105(21):7478-83. doi: 10.1073/pnas.0800693105.
New genes can originate by the combination of sequences from unrelated genes or their duplicates to form a chimeric structure. These chimeric genes often evolve rapidly, suggesting that they undergo adaptive evolution and may therefore be involved in novel phenotypes. Their functions, however, are rarely known. Here, we describe the phenotypic effects of a chimeric gene, sphinx, that has recently evolved in Drosophila melanogaster. We show that a knockout of this gene leads to increased male-male courtship in D. melanogaster, although it leaves other aspects of mating behavior unchanged. Comparative studies of courtship behavior in other closely related Drosophila species suggest that this mutant phenotype of male-male courtship is the ancestral condition because these related species show much higher levels of male-male courtship than D. melanogaster. D. melanogaster therefore seems to have evolved in its courtship behaviors by the recruitment of a new chimeric gene.
新基因可通过不相关基因或其复制序列的组合产生，形成嵌合结构。这些嵌合基因通常进化迅速，表明它们经历了适应性进化，因此可能与新的表型有关。然而，它们的功能却鲜为人知。在这里，我们描述了一个最近在黑腹果蝇中进化出的嵌合基因——斯芬克斯的表型效应。我们发现，敲除这个基因会导致黑腹果蝇中雄性对雄性求偶行为增加，尽管它并未改变交配行为的其他方面。对其他近缘果蝇物种求偶行为的比较研究表明，这种雄性对雄性求偶的突变表型是祖先状态，因为这些相关物种表现出比黑腹果蝇更高水平的雄性对雄性求偶行为。因此，黑腹果蝇似乎通过招募一个新的嵌合基因在求偶行为方面发生了进化。
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