Hare Todd A, O'Doherty John, Camerer Colin F, Schultz Wolfram, Rangel Antonio
Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA.
J Neurosci. 2008 May 28;28(22):5623-30. doi: 10.1523/JNEUROSCI.1309-08.2008.
To make sound economic decisions, the brain needs to compute several different value-related signals. These include goal values that measure the predicted reward that results from the outcome generated by each of the actions under consideration, decision values that measure the net value of taking the different actions, and prediction errors that measure deviations from individuals' previous reward expectations. We used functional magnetic resonance imaging and a novel decision-making paradigm to dissociate the neural basis of these three computations. Our results show that they are supported by different neural substrates: goal values are correlated with activity in the medial orbitofrontal cortex, decision values are correlated with activity in the central orbitofrontal cortex, and prediction errors are correlated with activity in the ventral striatum.
为了做出合理的经济决策，大脑需要计算几种不同的与价值相关的信号。这些信号包括目标价值，它衡量的是由所考虑的每个行动产生的结果所带来的预期奖励；决策价值，它衡量采取不同行动的净值；以及预测误差，它衡量与个体先前奖励预期的偏差。我们使用功能磁共振成像和一种新颖的决策范式来区分这三种计算的神经基础。我们的结果表明，它们由不同的神经基质支持：目标价值与内侧眶额皮质的活动相关，决策价值与中央眶额皮质的活动相关，预测误差与腹侧纹状体的活动相关。
