Ichikawa Hajime, Yamada Sayaka, Yoshioka Chiho, Tamaoki Toyoshi, Miura Syunichi, Suzuki Motoki, Makino Tetsuzou
Department of Radiology, Toyohashi Municipal Hospital.
Nihon Hoshasen Gijutsu Gakkai Zasshi. 2008 May 20;64(5):579-86. doi: 10.6009/jjrt.64.579.
We examined a method of quantitative analysis that used dynamic and static images to measure the Right-left (R-L) shunt ratio in lung perfusion scintigraphy.
A total of 18 patients suspected of having R-L shunt brought on by congenital heart disease were referred for lung perfusion scintigraphy from November 2005 to February 2007 at our hospital. We acquired anterior dynamic images, set ROIs in all fields of view, and measured the highest count. We acquired anterior and posterior static images of the chest and measured lung counts. We considered the highest count on dynamic images to be the total injection dose per one second, normalized the acquisition time of static images, and calculated the R-L shunt ratio. We weighed the measurement results of the R-L shunt ratio obtained by the dynamic method against that of the whole-body method by t-test and the least-squares method.
When we used a posterior static image in the dynamic method, we found that the coefficient of correlation (r) was 0.9831. The result of the t-test was that there was no significant difference at a level of significance of 1%.
We think the use of the dynamic method is possible in R-L shunt ratio measurement and can shorten the examination time.
我们研究了一种定量分析方法，该方法利用动态和静态图像来测量肺灌注闪烁显像中的左右（R-L）分流率。
2005年11月至2007年2月期间，我院共收治了18例疑似由先天性心脏病引起R-L分流的患者，并对其进行肺灌注闪烁显像检查。我们采集了前位动态图像，在所有视野中设置感兴趣区（ROI），并测量最高计数。我们采集了胸部的前后位静态图像，并测量肺部计数。我们将动态图像上的最高计数视为每秒的总注射剂量，对静态图像的采集时间进行归一化处理，并计算R-L分流率。我们通过t检验和最小二乘法，将动态法获得的R-L分流率测量结果与全身法的测量结果进行比较。
在动态法中使用后位静态图像时，我们发现相关系数（r）为0.9831。t检验结果表明，在1%的显著性水平上没有显著差异。
我们认为动态法可用于R-L分流率的测量，并且可以缩短检查时间。
