采用核磁共振技术对翻白草中两种新三萜类化合物进行结构测定。

Structural determination of two new triterpenoids from Potentilla discolor Bunge by NMR techniques.

作者信息

Yang Jie, Chen Xiao-Qing, Liu Xiao-Xiao, Cao Yuan, Lai Mao-Xiang, Wang Qiang

机构信息

Key laboratory of Modern Chinese Medicines (China pharmaceutical University), Ministry of Education, Nanjing, 210009, People's Republic of China.

出版信息

Magn Reson Chem. 2008 Aug;46(8):794-7. doi: 10.1002/mrc.2253.

DOI:10.1002/mrc.2253

PMID:18509870

Abstract

Two new pentacyclic triterpenoids, 3alpha, 30-dihydroxylup-20(29)-en-27-oic acid (1) and (20S)-3alpha, 29-dihydroxylupan-27-oic acid (2) were isolated from the whole herbs of Potentilla discolor Bunge. The structures of these two new compounds were elucidated, and complete assignments of the (1)H and (13)C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, (1)H-(1)HCOSY and ROESY).

摘要

从翻白草全草中分离得到两个新的五环三萜类化合物，3α,30 - 二羟基羽扇豆 - 20(29) - 烯 - 27 - 酸（1）和(20S) - 3α,29 - 二羟基羽扇豆 - 27 - 酸（2）。阐明了这两个新化合物的结构，并通过一维和二维核磁共振实验（HSQC、HMBC、¹H - ¹HCOSY和ROESY）完成了¹H和¹³C核磁共振光谱数据的全归属。