Volkotrub L P, Elizarova A T
Gig Sanit. 2008 Mar-Apr(2):35-40.
The impact of the content of iodine and other trace elements in the environmental objects of the Tomsk Region on the development of iodine-deficiency diseases was studied in children. Slightly sour soils and low soil humus levels in the Tomsk Region were ascertained to be conducive to low iodine content in soils and plants. As compared with the clarke of iodine in the lithosphere, the soils in the Tomsk Region were marked by low iodine levels, permitting it to be, in terms of endemic goiter, referred to as a biogeochemical province. The soils of rural areas in the Tomsk Region were characterized by the specific trace element composition--the high content of molybdenum and copper and the low level of zinc, which is a factor that is of importance in the development of endemic goiter. In children, daily dietary requirements for iodine were met at 60% of the normal levels, those for animal proteins at 50%, at the same time there was deficiency of amino acid tyrosine, the substrate involved in the synthesis of thyroid hormones. Endemic goiter occupies 80% in the structure of thyroid diseases. There is a considerable predominance of early goiter forms over severer ones. In terms of the level of ioduria, 64% of the examined children had mild iodine deficiency.
研究了托木斯克地区环境物体中碘及其他微量元素含量对儿童碘缺乏病发展的影响。已确定托木斯克地区土壤略酸且腐殖质含量低，这有利于土壤和植物中碘含量降低。与岩石圈中碘的克拉克值相比，托木斯克地区土壤碘含量低，就地方性甲状腺肿而言，可将其称为一个生物地球化学省。托木斯克地区农村土壤具有特定的微量元素组成——钼和铜含量高而锌含量低，这是地方性甲状腺肿发展中的一个重要因素。儿童每日碘的膳食需求量仅达到正常水平的60%，动物蛋白需求量达到50%，同时参与甲状腺激素合成的氨基酸酪氨酸缺乏。地方性甲状腺肿在甲状腺疾病结构中占80%。早期甲状腺肿形式比严重形式占相当大的优势。就尿碘水平而言，64%的受检儿童有轻度碘缺乏。
