Ding Hua-Ye, Yang Guang-Zhi
Department of Pathology, General Hospital of Beijing Military Command, Beijing 100700, China.
Zhonghua Bing Li Xue Za Zhi. 2008 Jan;37(1):31-4.
To study the clinical and pathological features of mucocele-like lesions in the breast.
Nine cases of mucocele-like lesions in the breast were reported for the morphological and immunohistochemical features, the differential diagnosis, and a literature review.
All nine cases were from female patients, aged 23 to 43 years (mean 34 years), clinically presented with palpable breast masses. Grossly, the lesions were multi-cystic with colloidal appearances. Histologically, the lesions consisted of multiple cysts filled with colloid, these cysts were lined with tubular, cuboidal or columnar epithelium. There were superimposed papillary epithelial hyperplasia in three cases and atypical ductal hyperplasia in one. Extravasated mucinous lakes were seen in the stroma, but without cellular component.
Mucocele-like lesions of the breast is a group of mostly benign disease, and the differential diagnosis should include mucinous carcinoma.
研究乳腺黏液囊肿样病变的临床及病理特征。
报告9例乳腺黏液囊肿样病变的形态学、免疫组化特征、鉴别诊断并进行文献复习。
9例均为女性患者，年龄23至43岁（平均34岁），临床表现为可触及的乳腺肿块。大体上，病变为多囊性，呈胶冻样外观。组织学上，病变由多个充满胶冻的囊肿组成，这些囊肿内衬管状、立方形或柱状上皮。3例有叠加的乳头状上皮增生，1例有非典型导管增生。间质可见黏液外渗湖，但无细胞成分。
乳腺黏液囊肿样病变是一组大多为良性的疾病，鉴别诊断应包括黏液癌。
