Zagólski Olaf, Gajda Mariusz
Specjalistyczne Centrum Diagnostyczno-Zabiegowe Medicina w Krakowie Oddział Otolaryngologiczny.
Przegl Lek. 2007;64(9):545-8.
Peritonsillar abscess (quinsy) is a complication of acute bacterial tonsillitis. Its treatment remains controversial. One element of controversy is the choice of antibiotics after surgical drainage of the abscess. Results of many studies support the resistance of grown bacteria to many antibiotics and the potential importance of anaerobic species in development of peritonsillar abscesses.
The purpose of the study was to investigate bacteriology of peritonsillar abscesses in the group of own patients in an attempt to establish optimal method of antibiotic treatment after drainage of the abscess.
Abscess material from 12 patients aged 20-43 years (mean: 31.5, s.d.: 6.8), 4 women and 8 men, with peritonsillar abscesses was obtained by aspiration and sent for aerobic and anaerobic cultures. All patients were subsequently treated with oral phenoxymethylpenicillin (4.5 million units per day) and metronidazole (1500 mg per day).
A total 18 bacterial isolates (9 anaerobic and 9 aerobic and facultative) were recovered, accounting for 1.5 isolate per specimen. Anaerobic bacteria only were present in 3 patients, aerobic and facultatives in 3, and mixed aerobic and anaerobic flora in 6. Single bacterial isolates were recovered in 6 infections. The predominant bacterial isolates were Streptococcus and Bacteroides. Recovery in all examined subjects was complete.
In the routine management of peritonsillar abscess, bacteriologic studies are unnecessary on initial presentation. It is, however, necessary to consider infection with anaerobes, hence we recommend penicillin and metronidazole as the antibiotic regimen of choice in the treatment of peritonsillar abscesses.
扁桃体周脓肿(脓性扁桃体炎)是急性细菌性扁桃体炎的一种并发症。其治疗仍存在争议。争议的一个方面是脓肿手术引流后抗生素的选择。许多研究结果表明,培养出的细菌对多种抗生素具有耐药性,并且厌氧菌在扁桃体周脓肿形成中可能具有重要作用。
本研究旨在调查本院患者扁桃体周脓肿的细菌学情况,试图确定脓肿引流后抗生素治疗的最佳方法。
通过穿刺获取12例年龄在20 - 43岁(平均31.5岁,标准差6.8岁)扁桃体周脓肿患者的脓肿材料,其中女性4例,男性8例,将其送去进行需氧和厌氧培养。所有患者随后接受口服青霉素V钾(每日450万单位)和甲硝唑(每日1500毫克)治疗。
共分离出18株细菌(9株厌氧菌、9株需氧菌和兼性厌氧菌),每个标本平均分离出1.5株。仅厌氧菌存在于3例患者中,需氧菌和兼性厌氧菌存在于3例患者中,需氧菌和厌氧菌混合菌群存在于6例患者中。6次感染中分离出单一细菌菌株。主要的细菌分离株为链球菌和拟杆菌属。所有检查对象均完全康复。
在扁桃体周脓肿的常规治疗中,初次就诊时无需进行细菌学检查。然而,有必要考虑厌氧菌感染,因此我们推荐青霉素和甲硝唑作为治疗扁桃体周脓肿的首选抗生素方案。