• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

梅毒:持续存在的公共卫生与诊断挑战。

Syphilis: continuing public health and diagnostic challenges.

作者信息

Daskalakis Demetre

机构信息

ACTU/Medicine, 550 First Avenue, BCD 5th Floor (Room 558), New York, NY 10016, USA.

出版信息

Curr HIV/AIDS Rep. 2008 May;5(2):72-7. doi: 10.1007/s11904-008-0012-6.

DOI:10.1007/s11904-008-0012-6
PMID:18510892
Abstract

As the "great imitator" of disease, syphilis, caused by the bacterium Treponema pallidum, continues to be a conceptually elusive condition that is surrounded by diagnostic ambiguity and clinical misunderstanding. Concurrent HIV infection adds further difficulty by introducing the oldest and most confusing medical conundrum into the socially and biologically complex situation of treating patients with a virus we are still only learning to manage. Syphilis continues to be a challenge to the health of men who have sex with men and people of color as infection rates continue to increase within these substantial subgroups living with HIV. As the resurgence of syphilis continues, a clear understanding of diagnostic testing, disease-staging paradigms, and treatment strategies are necessary for optimal management of the HIV co-infected patient.

摘要

作为疾病的“伟大模仿者”,由梅毒螺旋体引起的梅毒,仍然是一种在概念上难以捉摸的病症,它被诊断上的模糊性和临床误解所笼罩。同时感染艾滋病毒会带来更多困难,因为在我们仍在学习如何应对的病毒感染患者的复杂社会和生物学状况中,引入了最古老且最令人困惑的医学难题。梅毒对男男性行为者和有色人种的健康仍然构成挑战,因为在这些感染艾滋病毒的大量亚群体中,感染率持续上升。随着梅毒疫情的持续反弹,对于合并感染艾滋病毒的患者进行最佳管理,清晰了解诊断检测、疾病分期模式和治疗策略是必要的。

相似文献

1
Syphilis: continuing public health and diagnostic challenges.梅毒:持续存在的公共卫生与诊断挑战。
Curr HIV/AIDS Rep. 2008 May;5(2):72-7. doi: 10.1007/s11904-008-0012-6.
2
Syphilis.梅毒
Clin Dermatol. 2004 Nov-Dec;22(6):461-8. doi: 10.1016/j.clindermatol.2004.07.009.
3
The great imitator: malignant syphilis with hepatitis.伪装大师:恶性梅毒合并肝炎
Clin Dermatol. 2002 Mar-Apr;20(2):156-63. doi: 10.1016/s0738-081x(01)00249-8.
4
Emerging trends and persistent challenges in the management of adult syphilis.成人梅毒管理中的新趋势与持续挑战
BMC Infect Dis. 2015 Aug 19;15:351. doi: 10.1186/s12879-015-1028-3.
5
Cholangitis and pulmonary nodules in a clinical presentation of syphilis in an HIV-infected patient.一名感染HIV的患者梅毒临床表现中的胆管炎和肺结节
Int J STD AIDS. 2019 Jul;30(8):820-824. doi: 10.1177/0956462418823386. Epub 2019 May 2.
6
Syphilis: An Old Disease With Present-Day Implications.梅毒:一种具有当今影响的古老疾病。
N C Med J. 2016 Sep-Oct;77(5):365-8. doi: 10.18043/ncm.77.5.365.
7
Erythema multiforme triggered by Treponema pallidum infection in an HIV-infected patient.一名感染人类免疫缺陷病毒(HIV)的患者因梅毒螺旋体感染引发多形红斑。
Int J STD AIDS. 2018 Jan;29(1):99-102. doi: 10.1177/0956462417726203. Epub 2017 Aug 18.
8
Syphilis: antibiotic treatment and resistance.梅毒:抗生素治疗与耐药性。
Epidemiol Infect. 2015 Jun;143(8):1567-74. doi: 10.1017/S0950268814002830. Epub 2014 Oct 31.
9
The outcome of treatment of early latent syphilis and syphilis with undetermined duration in HIV-infected and HIV-uninfected patients.HIV感染和未感染HIV患者早期潜伏梅毒及病程不明梅毒的治疗结果
Int J STD AIDS. 2007 Dec;18(12):814-8. doi: 10.1258/095646207782717018.
10
Syphilis and HIV co-infection. Epidemiology, treatment and molecular typing of Treponema pallidum.梅毒与艾滋病毒合并感染。梅毒螺旋体的流行病学、治疗及分子分型
Dan Med J. 2015 Dec;62(12):B5176.

引用本文的文献

1
Case of Secondary Syphilis with Mucocutaneous, Articular, and Pulmonary Involvement in a 74-Year-Old Moroccan Man.74 岁摩洛哥男性患者的黏膜皮肤、关节和肺部受累二期梅毒病例。
Am J Case Rep. 2022 Oct 15;23:e937513. doi: 10.12659/AJCR.937513.
2
Seroprevalence and risk factors on Syphilis among blood donors in Chengdu, China,from 2005 to 2017.2005 年至 2017 年期间中国成都献血者梅毒血清流行率及危险因素分析。
BMC Infect Dis. 2019 Jun 10;19(1):509. doi: 10.1186/s12879-019-4128-7.
3
The disappearance of femoral head and neck resulting from extensive bone defect caused by secondary syphilis: a case report and literature review.

本文引用的文献

1
Symptomatic early neurosyphilis among HIV-positive men who have sex with men--four cities, United States, January 2002-June 2004.2002年1月至2004年6月美国四个城市中感染艾滋病毒的男同性恋者的有症状早期神经梅毒
MMWR Morb Mortal Wkly Rep. 2007 Jun 29;56(25):625-8.
2
Trends in primary and secondary syphilis among men who have sex with men in the United States.美国男男性行为者中一期和二期梅毒的流行趋势。
Am J Public Health. 2007 Jun;97(6):1076-83. doi: 10.2105/AJPH.2005.070417. Epub 2007 Apr 26.
3
Performance of CAPTIA SelectSyph-G enzyme-linked immunosorbent assay in syphilis testing of a high-risk population: analysis of discordant results.
二期梅毒所致广泛骨缺损导致股骨头和颈消失:1例报告及文献复习
BMC Musculoskelet Disord. 2018 Jul 25;19(1):251. doi: 10.1186/s12891-018-2152-1.
4
A case of rupioid syphilis.一例蛎壳状梅毒病例。
JAAD Case Rep. 2016 Mar 17;2(2):141-3. doi: 10.1016/j.jdcr.2016.01.006. eCollection 2016 Mar.
5
Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients.HIV感染患者口腔二期梅毒的临床谱
J Sex Transm Dis. 2013;2013:892427. doi: 10.1155/2013/892427. Epub 2012 Dec 17.
6
Evaluation of the recombinant protein TpF1 of Treponema pallidum for serodiagnosis of syphilis.梅毒螺旋体重组蛋白TpF1用于梅毒血清学诊断的评估。
Clin Vaccine Immunol. 2013 Oct;20(10):1563-8. doi: 10.1128/CVI.00122-13. Epub 2013 Aug 14.
7
Pseudolymphomatous luetic lymphadenitis associated with B cell clonality.与B细胞克隆性相关的假淋巴瘤性梅毒淋巴结炎
Virchows Arch. 2012 Feb;460(2):231-5. doi: 10.1007/s00428-011-1189-4. Epub 2012 Jan 19.
8
The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease.背向散射干涉测量术作为一种体外临床诊断工具,用于传染病的血清学诊断。
Analyst. 2010 Jul;135(7):1535-7. doi: 10.1039/c0an00098a. Epub 2010 Apr 22.
9
Differential regulation of the multiple flagellins in spirochetes.螺旋体中多种鞭毛蛋白的差异调控。
J Bacteriol. 2010 May;192(10):2596-603. doi: 10.1128/JB.01502-09. Epub 2010 Mar 19.
CAPTIA SelectSyph - G酶联免疫吸附试验在高危人群梅毒检测中的性能:不一致结果分析
J Clin Microbiol. 2007 Jun;45(6):1794-7. doi: 10.1128/JCM.02259-06. Epub 2007 Apr 18.
4
Syphilis and HIV infection: an update.梅毒与艾滋病毒感染:最新情况
Clin Infect Dis. 2007 May 1;44(9):1222-8. doi: 10.1086/513427. Epub 2007 Mar 14.
5
Syphilis and other sexually transmitted diseases in HIV infection.HIV感染中的梅毒及其他性传播疾病
Top HIV Med. 2007 Feb-Mar;15(1):11-6.
6
Déjà vu all over again: when to perform a lumbar puncture in HIV-infected patients with syphilis.似曾相识之感再度袭来:何时对感染HIV的梅毒患者进行腰椎穿刺。
Sex Transm Dis. 2007 Mar;34(3):145-6. doi: 10.1097/01.olq.0000251204.18648.15.
7
Impact of syphilis infection on HIV viral load and CD4 cell counts in HIV-infected patients.梅毒感染对HIV感染者的HIV病毒载量及CD4细胞计数的影响。
J Acquir Immune Defic Syndr. 2007 Mar 1;44(3):356-9. doi: 10.1097/QAI.0b013e31802ea4c6.
8
Increases in sexually transmitted infections and sexual risk behaviour without a concurrent increase in HIV incidence among men who have sex with men in San Francisco: a suggestion of HIV serosorting?旧金山男男性行为者中性传播感染和性风险行为增加,但艾滋病毒发病率并未同时上升:这是否暗示了艾滋病毒血清型分类?
Sex Transm Infect. 2006 Dec;82(6):461-6. doi: 10.1136/sti.2006.019950.
9
Analysis of HIV-1 sequences before and after co-infecting syphilis.梅毒合并感染前后的HIV-1序列分析。
Microbes Infect. 2006 Nov-Dec;8(14-15):2872-9. doi: 10.1016/j.micinf.2006.09.003. Epub 2006 Oct 23.
10
Barebacking websites: electronic environments for reducing or inducing HIV risk.无保护肛交网站:降低或诱发艾滋病毒风险的电子环境。
AIDS Care. 2006 Nov;18(8):990-7. doi: 10.1080/09540120500521137.