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参加教会活动在墨西哥裔美国老年人的抑郁症状与认知功能之间的关联中起中介作用。

Church attendance mediates the association between depressive symptoms and cognitive functioning among older Mexican Americans.

作者信息

Reyes-Ortiz Carlos A, Berges Ivonne M, Raji Mukaila A, Koenig Harold G, Kuo Yong-Fang, Markides Kyriakos S

机构信息

Sealy Center on Aging, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555-0460, USA.

出版信息

J Gerontol A Biol Sci Med Sci. 2008 May;63(5):480-6. doi: 10.1093/gerona/63.5.480.

Abstract

BACKGROUND

The objective of this study was to examine how the effect of depressive symptoms on cognitive function is modified by church attendance.

METHODS

We used a sample of 2759 older Mexican Americans. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) at baseline, 2, 5, 7, and 11 years of follow-up. Church attendance was dichotomized as frequent attendance (e.g., going to church at least once a month) versus infrequent attendance (e.g., never or several times a year). Depressive symptoms were assessed by the Center for Epidemiologic Studies Depression Scale (CES-D; score >or=16 vs <16). General linear mixed models with time-dependent covariates were used to explore cognitive change at follow-up.

RESULTS

In unadjusted models, infrequent church attendees had a greater decline in MMSE scores (drop of 0.151 points more each year, standard error [SE] = 0.02, p <.001) compared to frequent church attendees; participants having CES-D scores >or=16 also had greater declines in MMSE scores (drop of 0.132 points more each year, SE = 0.03, p <.001) compared to participants with CES-D score <16 at follow-up. In fully adjusted models, a significant Church attendance x CES-D x Time interaction (p =.001) indicated that, among participants with CES-D scores >or=16, infrequent church attendees had greater decline in MMSE scores (drop of 0.236 points more each year, SE = 0.05, p <.001) compared to frequent church attendees at follow-up.

CONCLUSION

Church attendance appears to be beneficial for maintaining cognitive function of older persons. Church attendance moderates the impact of clinically relevant depressive symptoms on subsequent cognitive function.

摘要

背景

本研究的目的是探讨参加教会活动如何改变抑郁症状对认知功能的影响。

方法

我们选取了2759名墨西哥裔美国老年人作为样本。在基线、随访2年、5年、7年和11年时,使用简易精神状态检查表(MMSE)评估认知功能。参加教会活动被分为经常参加(例如,每月至少去教堂一次)和不经常参加(例如,从不或每年去几次)。通过流行病学研究中心抑郁量表(CES-D;得分≥16分与<16分)评估抑郁症状。使用具有时间依存性协变量的一般线性混合模型来探索随访期间的认知变化。

结果

在未调整的模型中,与经常参加教会活动的人相比,不经常参加教会活动的人MMSE得分下降幅度更大(每年多下降0.151分,标准误[SE]=0.02,p<0.001);在随访时,CES-D得分≥16分的参与者与CES-D得分<16分的参与者相比,MMSE得分下降幅度也更大(每年多下降0.132分,SE=0.03,p<0.001)。在完全调整的模型中,教会活动×CES-D×时间的显著交互作用(p=0.001)表明,在CES-D得分≥16分的参与者中,与随访时经常参加教会活动的人相比,不经常参加教会活动的人MMSE得分下降幅度更大(每年多下降0.236分,SE=0.05,p<0.001)。

结论

参加教会活动似乎有利于维持老年人的认知功能。参加教会活动可减轻临床相关抑郁症状对后续认知功能的影响。

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