身体健康与终身认知变化。
Physical fitness and lifetime cognitive change.
作者信息
Deary Ian J, Whalley Lawrence J, Batty G David, Starr John M
机构信息
Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, UK.
出版信息
Neurology. 2006 Oct 10;67(7):1195-200. doi: 10.1212/01.wnl.0000238520.06958.6a.
OBJECTIVE
To test the hypothesis that physical fitness is associated with more successful cognitive aging.
METHODS
Surviving participants (N = 460) of the Scottish Mental Survey of 1932 were tested on the same general cognitive test at age 11 and 79 years. Measures of grip strength, 6-meter walk time, and lung function (forced expiratory volume from the lungs in 1 second [FEV1]) were assessed at age 79 years.
RESULTS
A latent physical fitness trait, derived by principal components analysis of the three fitness measures, was significantly associated with successful cognitive aging. Cognitive score at age 11, sex, social class, and APOE-epsilon4 genotype were included as covariables. Higher childhood IQ was associated with better lung function in old age.
CONCLUSIONS
Physical fitness is associated with cognitive reserve. Intervention studies aimed at making older people fitter are good candidates to improve cognitive aging.
目的
检验体能与更成功的认知衰老相关这一假设。
方法
1932年苏格兰精神调查的幸存参与者（N = 460）在11岁和79岁时接受了相同的一般认知测试。在79岁时评估握力、6米步行时间和肺功能（一秒钟用力呼气量[FEV1]）。
结果
通过对三项体能指标进行主成分分析得出的潜在体能特质与成功的认知衰老显著相关。将11岁时的认知得分、性别、社会阶层和APOE-ε4基因型作为协变量。儿童时期较高的智商与老年时较好的肺功能相关。
结论
体能与认知储备相关。旨在使老年人更健康的干预研究有望改善认知衰老。
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