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相对反应性(rho):受体分化新方法的批判性分析。

Relative responsiveness (rho): a critical analysis of a new method in receptor differentiation.

作者信息

Jurkiewicz A, Abdo A O, Jurkiewicz N H, Guedes A O, Souccar C

出版信息

Gen Pharmacol. 1976 Aug;7(2-3):93-101. doi: 10.1016/0306-3623(76)90042-2.

DOI:10.1016/0306-3623(76)90042-2
PMID:185120
Abstract

The rho ratio, which measures the capability of a receptor system to induce a maximal contraction after saturation by a full agonist was analysed from the standpoint of its variability considering the values obtained either for a given receptor system in the same type of preparation or for different types of preparation. This variability was discussed on the grounds of receptor theory, as the basis for a new method in receptor differentiation.

摘要

rho比值衡量的是受体系统在被完全激动剂饱和后诱导最大收缩的能力。我们从变异性的角度对其进行了分析,考虑了在同一类型制剂中针对给定受体系统所获得的值,以及针对不同类型制剂所获得的值。基于受体理论讨论了这种变异性,将其作为受体分化新方法的基础。

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