Berthéas M F, Frappaz D, Elian J, Brizard C, Brunon J, Freycon F
Laboratoire d'hématologie cytogénétique, CHU Saint-Etienne, hôpital Nord, Saint-Priest-en-Jarez, France.
Pediatrie. 1991;46(1):65-9.
The authors review the literature concerning chromosomal abnormalities in childhood brain tumors: medulloblastomas, ependymomas, and gliomas of low and high grade. Though these technics require further development, they highlight the role of cytogenetic modification in oncogenesis of brain tumors.
作者回顾了有关儿童脑肿瘤(髓母细胞瘤、室管膜瘤以及低级别和高级别胶质瘤)染色体异常的文献。尽管这些技术需要进一步发展,但它们凸显了细胞遗传学改变在脑肿瘤发生过程中的作用。