Morimoto M, Ohno T, Yamashita Y, Honda M, Asada S
Department of Surgery, Takasago Municipal Hospital, Hyogo, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1991 Feb;39(2):245-50.
Synchronous double carcinoma of the lung and the esophagus is extremely rare disease. In Japan, 13 cases have reported by Abo and only 10 clinical cases have been documented so far. We describe two cases of synchronous double carcinoma of the lung and the esophagus. Case 1. A 74-year-old man was admitted to our hospital because of the abnormal shadow of the chest X-ray film. Left upper lobectomy was carried out for the lung carcinoma. Because of dysphagia after surgery, upper GI series and endoscopic biopsy were performed, and midesophageal carcinoma was revealed. Radical operation of the esophageal carcinoma was performed 2 months after the first operation. Pathological diagnosis of the lung tumor and the esophageal tumor were well differentiated adenocarcinoma and moderately differentiated squamous cell carcinoma respectively and both of them were early cancer. After 22 months of the second operation, he is doing well. Case 2. a 66-year-old man was operated on because of the esophageal carcinoma in other hospital. Abnormal shadow appeared in his X-ray film 10 months after operation. Although he received chemotherapy as metastatic lung cancer, bronchoscopic examination revealed it adenocarcinoma. We performed segmental lobectomy to him 17 months after the first operation. Pathological diagnosis was large cell carcinoma of the lung. He is also doing well 18 months after the second operation.
肺与食管同时发生的双原发癌是一种极为罕见的疾病。在日本，阿保报道过13例，迄今为止仅有10例临床病例有文献记载。我们报告两例肺与食管同时发生的双原发癌。病例1：一名74岁男性因胸部X光片出现异常阴影入住我院。对肺癌患者实施了左上叶切除术。术后因吞咽困难，进行了上消化道造影和内镜活检，结果显示为食管中段癌。在第一次手术后2个月对食管癌实施了根治性手术。肺肿瘤和食管肿瘤的病理诊断分别为高分化腺癌和中分化鳞状细胞癌，二者均为早期癌。第二次手术后22个月，他情况良好。病例2：一名66岁男性因食管癌在其他医院接受了手术。术后10个月其X光片出现异常阴影。尽管他作为转移性肺癌接受了化疗，但支气管镜检查显示为腺癌。在第一次手术后17个月对他实施了肺段切除术。病理诊断为肺大细胞癌。第二次手术后18个月，他情况也良好。
