Beukers M, Boddeke E W
Division of Medicinal Chemistry, Gorlaeus Laboratories, Leiden, The Netherlands.
Pharm Weekbl Sci. 1991 Feb 22;13(1):7-12. doi: 10.1007/BF01963877.
Long-term potentiation is widely used as a model for memory formation. Recently, much information concerning this topic like the involvement of protein kinase C, arachidonic acid and N-methyl-D-aspartate receptors has been reported. In this review recent discoveries concerning long-term potentiation and the pharmacological implications for the development of cognition-enhancing drugs are discussed.
长期增强作用被广泛用作记忆形成的模型。最近,已经报道了许多关于这个主题的信息,如蛋白激酶C、花生四烯酸和N-甲基-D-天冬氨酸受体的参与情况。在这篇综述中,讨论了关于长期增强作用的最新发现以及对开发认知增强药物的药理学意义。