Beukers M, Boddeke E W
Division of Medicinal Chemistry, Gorlaeus Laboratories, Leiden, The Netherlands.
Pharm Weekbl Sci. 1991 Feb 22;13(1):7-12. doi: 10.1007/BF01963877.
Long-term potentiation is widely used as a model for memory formation. Recently, much information concerning this topic like the involvement of protein kinase C, arachidonic acid and N-methyl-D-aspartate receptors has been reported. In this review recent discoveries concerning long-term potentiation and the pharmacological implications for the development of cognition-enhancing drugs are discussed.