Dalen T, Coebergh J W, Casparie M K, Gimbrère C H, Hoekstra H J, Van Geel B N, Coevorden F V, Hennipman A
Dutch Soft Tissue Sarcoma Group Vereniging van Integrale Kanker Centra Utrecht The Netherlands.
Sarcoma. 2001;5(1):5-8. doi: 10.1080/13577140120048881.
Purpose. In the clinical work-up of a retroperitoneal mass, the diagnosis of soft tissue sarcoma is often not considered. Incidence rates of various malignant and benign retroperitoneal tumours were studied to determine the incidence of soft tissue sarcoma in comparison with other neoplasms in the retroperitoneal space.Method. Nation-wide data on retroperitoneal tumours, collected prospectively over a 5-year period (1 January 1989- 1 January 1994), were supplied by the Netherlands Cancer Registry and The Dutch Network and National Database for Pathology.Results. Seven hundred and six patients with a primary retroperitoneal neoplasm were identified; 566 patients had a malignant tumour (80%). A soft tissue sarcoma (STS) was the most frequently diagnosed malignant tumour (n = 192), The agestandardised incidence of retroperitoneal STS was 2.5 per million person-years. The male/female ratio for STS was 0.73. In females, STS comprised 41%of all malignant retroperitoneal tumours, carcinoma of unknown primary tumour site (CUP) comprised 31%, and malignant lymphomas (ML) comprised 22%, whereas in males these values were 28% (STS), 30% (CUP), and 32% (ML), respectively.Discussion. Soft tissue sarcomas, albeit rare, are relatively common primary tumours in the retroperitoneum, especially in women.
目的。在对腹膜后肿块进行临床检查时，软组织肉瘤的诊断往往未被考虑。研究各种恶性和良性腹膜后肿瘤的发病率，以确定软组织肉瘤与腹膜后间隙其他肿瘤相比的发病率。
方法。荷兰癌症登记处以及荷兰病理学网络和国家数据库提供了在5年期间（1989年1月1日至1994年1月1日）前瞻性收集的全国腹膜后肿瘤数据。
结果。共确定了706例原发性腹膜后肿瘤患者；566例患有恶性肿瘤（80%）。软组织肉瘤（STS）是最常被诊断出的恶性肿瘤（n = 192），腹膜后STS的年龄标准化发病率为每百万人年2.5例。STS的男/女比例为0.73。在女性中，STS占所有恶性腹膜后肿瘤的41%，原发肿瘤部位不明的癌（CUP）占31%，恶性淋巴瘤（ML）占22%，而在男性中，这些比例分别为28%（STS）、30%（CUP）和32%（ML）。
讨论。软组织肉瘤虽然罕见，但在腹膜后是相对常见的原发性肿瘤，尤其是在女性中。
