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[腰椎间盘突出症手术后感觉传入缺失所致慢性坐骨神经痛:临床与治疗方面。附110例病例]

[Chronic sciatalgia caused by sensitive deafferentiation following surgery for lumbar disk hernia: clinical and therapeutic aspects. Apropos of 110 patients].

作者信息

Blond S, Armignies P, Parker F, Dupard T, Guieu J D, Duquesnoy B, Christiaens J L

机构信息

Service de Neurochirurgie A, Hôpital B, C.H.R.U., Lille.

出版信息

Neurochirurgie. 1991;37(2):86-95.

PMID:1852244
Abstract

Sensitive deafferentation is a well recognized entity which has changed the therapeutic approach of some kinds of chronic post operative sciatalgia. It mainly occurs related with a long story of radicular pain and the responsibility of so-called epidural fibrosis has to be discussed. The case records of 110 consecutive patients with deafferentation sciatalgia were reviewed and the clinical data precised: chronic and lasting burning pain with acute nightly paroxysms and sensitive alterations at objective examination. Neuroradiological explorations eliminated the possibility of recurrent disc herniation and neurophysiological tests assessed the chronic radicular suffering and the degree of lemniscal degeneration. After medical treatment (analgesic drugs with central tropism), a strict clinical assessment of pain intensity allowed optimal choice of the technique of neurostimulation: transcutaneous electrical stimulation (51 patients) and/or spinal cord stimulation (59 patients). The efficacy of transcutaneous stimulation (40 excellent and good results) was most often related to its continuous utilisation with a short post-effect. Its side-effects and the frequency of multiradicular involvement lead to spinal cord stimulation. With a mean follow-up period of 37 months, the pain relief was considered as excellent in 51.5%, good in 38% and poor in 8.5% of the patients. One patient had a negative test and was not definitively implanted. Another case failed to respond to stimulation. The clinical and technical complication of the method are reported.

摘要

感觉性去传入是一种已得到充分认识的情况,它改变了某些慢性术后坐骨神经痛的治疗方法。它主要与长期的神经根性疼痛有关,所谓硬膜外纤维化的作用必须加以探讨。回顾了110例连续性感觉性去传入性坐骨神经痛患者的病历,并精确了临床资料:慢性持续性灼痛伴夜间急性发作以及客观检查时的感觉改变。神经放射学检查排除了复发性椎间盘突出的可能性,神经生理学测试评估了慢性神经根性病变及内侧丘系退变程度。在药物治疗(具有中枢作用的镇痛药)后,对疼痛强度进行严格的临床评估有助于优化神经刺激技术的选择:经皮电刺激(51例患者)和/或脊髓刺激(59例患者)。经皮刺激的疗效(40例效果优良)大多与其持续使用及后效应短有关。其副作用及多节段受累的频率促使采用脊髓刺激。平均随访37个月,51.5%的患者疼痛缓解被认为优,38%为良,8.5%为差。1例患者测试阴性,未最终植入。另1例对刺激无反应。报告了该方法的临床和技术并发症。

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