Grosvenor T, Perrigin D, Perrigin J, Quintero S
School of Optometry, Indiana University, Bloomington.
Optom Vis Sci. 1991 May;68(5):385-9. doi: 10.1097/00006324-199105000-00011.
Conventionally fitted Paraperm O2plus contact lenses were worn for 44 months by 23 myopic children, who discontinued lens wear for 2.5 months and then resumed lens wear with Fluoroperm 30 lenses for a period of 8 months. Mean changes in myopia were: (1) an increase of 0.76 D during the initial 44 months of lens wear, (2) a further increase of 0.27 D during the 2.5 months when lenses were not worn, and (3) a decrease of 0.02 D during the 8-month period of Fluoroperm 30 lens wear. These results show that the effect of rigid gas-permeable lenses on myopia progression is diminished if lens wear is discontinued; however, the mean increase in myopia for these children was significantly less than would have been expected if glasses had been worn for the entire 54.5-month period. The results after discontinuation and then resumption of lens wear show that the effect of contact lenses in controlling the progression of myopia could not be accounted for entirely on the basis of corneal flattening as measured by the keratometer, therefore reinforcing the conclusion that corneal flattening due to rigid lens wear takes place primarily at the corneal apex, rather than in the zone of the cornea measured by the keratometer.
23名近视儿童佩戴传统验配的Paraperm O2plus隐形眼镜44个月，之后停戴2.5个月，然后换戴Fluoroperm 30隐形眼镜8个月。近视的平均变化情况如下：(1) 在最初佩戴隐形眼镜的44个月里近视增加0.76 D，(2) 在停戴隐形眼镜的2.5个月里近视进一步增加0.27 D，(3) 在佩戴Fluoroperm 30隐形眼镜的8个月期间近视减少0.02 D。这些结果表明，如果停止佩戴硬性透气性隐形眼镜，其对近视进展的影响会减弱；然而，这些儿童近视的平均增加幅度明显小于如果在整个54.5个月期间一直佩戴眼镜所预期的增加幅度。停戴后再恢复佩戴隐形眼镜的结果表明，隐形眼镜控制近视进展的效果不能完全根据角膜曲率计测量的角膜扁平化来解释，因此强化了这样的结论，即硬性隐形眼镜佩戴导致的角膜扁平化主要发生在角膜顶点，而不是在角膜曲率计测量的角膜区域。
