Perrigin J, Perrigin D, Quintero S, Grosvenor T
College of Optometry, University of Houston, Texas.
Optom Vis Sci. 1990 Oct;67(10):764-9. doi: 10.1097/00006324-199010000-00003.
One hundred myopic children between the ages of 8 and 13 years were fitted with Paraperm O2plus silicone-acrylate contact lenses. After 3 years of lens wear, the mean increase in myopia for the 56 subjects remaining in the study was 0.48 D (+/- 0.70) D as compared with 1.53 (+/- 0.81) D for a group of spectacle-wearing myopes matched for initial age and initial refractive error. The mean change in corneal refracting power for the contact lens wearers was a decrease (corneal flattening) of 0.37 (+/- 0.32) D. Assuming that little or no corneal change would have occurred in the absence of the contact lenses, we may conclude that corneal flattening (as measured by the keratometer) accounts for less than half of the effect of contact lenses in controlling myopia progression. A possible explanation for this disparity is that although the keratometer provides a valid measurement of corneal refracting power for a "normal" cornea, it fails to provide a valid measurement for a cornea that has been flattened by wearing a contact lens.
100名年龄在8至13岁之间的近视儿童佩戴了Paraperm O2plus硅丙烯酸酯隐形眼镜。戴镜3年后，研究中剩余的56名受试者近视平均增加0.48 D（±0.70 D），而一组初始年龄和初始屈光不正相匹配的戴框架眼镜的近视患者近视平均增加1.53（±0.81）D。隐形眼镜佩戴者角膜屈光力的平均变化为降低（角膜变平）0.37（±0.32）D。假设在不佩戴隐形眼镜的情况下角膜几乎没有变化，我们可以得出结论，（通过角膜曲率计测量的）角膜变平在控制近视进展中所起的作用不到隐形眼镜作用的一半。这种差异的一个可能解释是，尽管角膜曲率计能对“正常”角膜的角膜屈光力进行有效测量，但对于因佩戴隐形眼镜而变平的角膜，它无法进行有效测量。
