Xiong Jianyu, Li Yuncang, Wang Xiaojian, Hodgson Peter, Wen Cui'e
Centre for Material and Fibre Innovation, Deakin University, Geelong, VIC 3217, Australia.
Acta Biomater. 2008 Nov;4(6):1963-8. doi: 10.1016/j.actbio.2008.04.022. Epub 2008 May 11.
A porous Ti-18 at.%Nb-4 at.%Sn (hereafter, Ti-18Nb-4Sn) alloy was prepared by powder metallurgy. The porous structures were examined by scanning electron microscopy and the phase constituents were analysed by X-ray diffraction. Mechanical properties of the porous alloy were investigated using a compressive test. To enhance the bioactivity of the alloy surface, alkali-heat treatment was used to modify the surface. The bioactivity of the pre-treated alloy sample was investigated using a biomimetic process by soaking the sample into simulated body fluid (SBF). Results indicate that the elastic modulus and plateau stress of the porous Ti-18Nb-4Sn alloy decrease with decreasing relative density. The mechanical properties of the porous alloy can be tailored to match those of human bone. After soaking in SBF for 7 days, a hydroxyapatite layer formed on the surface of the pre-treated porous Ti-18Nb-4Sn alloy. The pre-treated porous Ti-18Nb-4Sn alloy therefore has the potential to be a bioactive implant material.
采用粉末冶金法制备了孔隙率为18 at.%Nb-4 at.%Sn的多孔Ti合金（以下简称Ti-18Nb-4Sn合金）。通过扫描电子显微镜对多孔结构进行了观察，并用X射线衍射分析了相组成。采用压缩试验研究了多孔合金的力学性能。为提高合金表面的生物活性，采用碱热处理对表面进行改性。通过将预处理后的合金样品浸泡在模拟体液（SBF）中，利用仿生过程研究了预处理合金样品的生物活性。结果表明，多孔Ti-18Nb-4Sn合金的弹性模量和平台应力随相对密度的降低而减小。多孔合金的力学性能可进行调整以匹配人体骨骼的力学性能。在SBF中浸泡7天后，预处理后的多孔Ti-18Nb-4Sn合金表面形成了羟基磷灰石层。因此，预处理后的多孔Ti-18Nb-4Sn合金有潜力成为一种生物活性植入材料。
