Takahashi Maki, Seimiya Yukio M, Seki Yoshihisa, Yamada Manabu
Iwate Prefecture Central Livestock Hygiene Service Center, Takizawa-mura, Iwate, Japan.
J Vet Med Sci. 2008 May;70(5):497-500. doi: 10.1292/jvms.70.497.
A piglet developed respiratory distress followed by difficulty in standing and unsteady gait. The lesions were characterized by polioencephalomyelitis with the predominant distribution in the brain stem, as well as lymphocyte depletion and histiocyte infiltration with cytoplasmic inclusion bodies in the lymphoid tissues throughout the body and interstitial pneumonia. Porcine teschovirus (PTV) antigens were found in the former lesions and porcine circovirus 2 (PCV2) in the latter two lesions. PTV genes were detected from the diencephalon. The results suggest that the piglet was concurrently affected with polioencephalomyelitis due to PTV and postweaning multisystemic wasting syndrome (PMWS) associated with PCV2. They also suggest that the immunosuppressive condition developing in PMWS may have facilitated the infection of the brain with PTV.
一只仔猪出现呼吸窘迫，随后站立困难且步态不稳。病变特征为脑脊髓灰质炎，主要分布于脑干，以及全身淋巴组织中的淋巴细胞耗竭、组织细胞浸润和细胞质内包涵体，还有间质性肺炎。在前述病变中发现了猪捷申病毒（PTV）抗原，在后两种病变中发现了猪圆环病毒2型（PCV2）。从间脑中检测到了PTV基因。结果表明，该仔猪同时感染了由PTV引起的脑脊髓灰质炎和与PCV2相关的断奶后多系统消耗综合征（PMWS）。结果还表明，PMWS中出现的免疫抑制状况可能促进了PTV对脑部的感染。
