Harania Reena Shah, Karuru Jane, Nelson Mark, Stebbing Justin
Aga Khan University Hospital, Nairobi, Kenya.
AIDS. 2008 Jun 19;22(10):1221-2. doi: 10.1097/QAD.0b013e32830162a8.
There are few data regarding hepatitis and HIV coinfection in Africa. In 378 HIV seropositive individuals in Nairobi, 23 (6%) were hepatitis B virus (HBV) and HIV coinfected, four (1%) were hepatitis C virus (HCV) and HIV coinfected and one patient was infected with all three viruses. Coinfected individuals were more likely to be men and older; a lack of HBV vaccination was a risk factor for HIV/HBV coinfection (P = 0.001) and tenofovir containing regimens appeared most effective at reducing HBV viral load.
关于非洲地区肝炎与艾滋病毒合并感染的数据很少。在内罗毕的378名艾滋病毒血清阳性个体中，23人（6%）为乙型肝炎病毒（HBV）和艾滋病毒合并感染，4人（1%）为丙型肝炎病毒（HCV）和艾滋病毒合并感染，1名患者感染了所有三种病毒。合并感染的个体更可能为男性且年龄较大；未接种乙肝疫苗是艾滋病毒/乙肝病毒合并感染的一个危险因素（P = 0.001），含替诺福韦的治疗方案似乎在降低乙肝病毒载量方面最有效。
