Thomson Vivien, Pialat Jean-Baptiste, Gay Frédéric, Coulon Agnès, Voloch Alain, Granier Anne, Guérin Jean-Claude, Viallon Magalie, Berthezene Yves
Service de Radiologie, Hôpital de la Croix-Rousse, Lyon, France.
Am J Clin Oncol. 2008 Jun;31(3):285-92. doi: 10.1097/COC.0b013e31815e3ff4.
To evaluate 3D Volumetric Interpolated Breath-hold Examination (VIBE) whole-body MRI (WB-MRI) acquisition for the metastases staging.
Thirty-two consecutive patients with solid tumor were examined from head to feet before and after contrast injection. An automatic subtraction occurred between the 2 series of images. WB-MRI was compared with conventional staging techniques (CT, scintigraphy, brain MRI, and whole-body PET in 4 cases).
WB-MRI and the reference techniques depicted metastases in 25 patients. WB-MRI depicted more bone lesions in the spine, pelvis, skull, femur, and tibia, whereas scintigraphy detected more rib lesions. WB-MRI depicted 27 cerebral metastases, whereas brain MRI depicted 40 cerebral metastases. WB-MRI depicted a total of 8 hepatic metastases, 8 adrenal lesions, and conventional staging 7 hepatic metastases and 10 adrenal lesions. WB-MRI examination depicted lung metastases in 10 patients, and CT examination in 13 patients.
The results of this study indicate that WB-MRI is a feasible and promising technique for tumor staging.
评估三维容积内插屏气检查（VIBE）全身磁共振成像（WB-MRI）用于转移灶分期的情况。
对32例连续的实体瘤患者在注射对比剂前后进行从头到脚的检查。两组图像之间自动进行减法运算。将WB-MRI与传统分期技术（4例患者行CT、骨闪烁显像、脑MRI和全身PET）进行比较。
WB-MRI和参考技术在25例患者中发现了转移灶。WB-MRI在脊柱、骨盆、颅骨、股骨和胫骨中发现了更多的骨转移灶，而骨闪烁显像检测到更多的肋骨转移灶。WB-MRI发现27个脑转移灶，而脑MRI发现40个脑转移灶。WB-MRI共发现8个肝转移灶、8个肾上腺病灶，传统分期发现7个肝转移灶和10个肾上腺病灶。WB-MRI检查在10例患者中发现了肺转移灶，CT检查在13例患者中发现了肺转移灶。
本研究结果表明，WB-MRI是一种用于肿瘤分期的可行且有前景的技术。
