Heiberg A, Lofterød B
Frambu Helsesenter, Siggerud.
Nord Med. 1991;106(6-7):189-90.
In the multifactorial aetiology of childhood obesity, Prader-Willi syndrome (PWS), probably is the commonest cause of abnormal overweight. The estimated prevalence of which is 1 in 10,000-25,000. Most of the approximately 75 known cases in Norway concern patients under 20 years of age. Recent years have witnessed a marked increase in our knowledge of the genetic aspects of PWS. Treatment needs to be multidisciplinary in approach, and to be started early to forestall a number of organic complications associated with reduced appetite control and significant overweight.
在儿童肥胖的多因素病因中，普拉德-威利综合征（PWS）可能是超重异常最常见的原因。其估计患病率为万分之一至两万五千分之一。挪威已知的约75例病例大多涉及20岁以下的患者。近年来，我们对PWS遗传方面的认识有了显著提高。治疗需要采用多学科方法，并尽早开始，以预防与食欲控制降低和显著超重相关的一系列器官并发症。
