Brozek Rafal, Rogalewicz Rafal, Koczorowski Ryszard, Voelkel Adam
Dental Clinic of MSWiA Hospital, ul. Dojazd 34, Poznan 60-631, Poland.
J Environ Monit. 2008 Jun;10(6):770-4. doi: 10.1039/b719825f. Epub 2008 Apr 21.
Biocompatibility constitutes the most fundamental requirement with respect to all dental materials to be applied within the oral cavity. In its environment, various toxic compounds may be released by dental materials which pose potential threats to the patient's health. Due to the fact that dentures remain in the oral cavity for a very long time, a detailed examination and verification of prosthetic materials with a view to their toxicity seems to be essential. By using very sensitive measurement techniques such as gas chromatography, one may determine which compounds are released by these materials. The aim of this paper was to determine the influence of various denture cleansers on the release of organic compounds from four soft dental materials used in prosthetics for lining dentures. These materials when placed in commonly used disinfectants (Corega Tabs, sodium hypochlorite, chlorhexidine, hydrogen peroxide), as well as in artificial saliva, produced 13 chemical compounds such as monomers (methyl methacrylate, ethyl methacrylate, dodecyl methacrylate), plasticizers (dibutyl phthalate, diethyl phthalate, tributyl acetylcitrate) and others (e.g. benzophenone). A comparison of chemical compounds released from acrylic-based materials and those released from silica-based materials demonstrated that acrylic-based materials are less resistant to disinfectants.
生物相容性是所有用于口腔内的牙科材料最基本的要求。在口腔环境中，牙科材料可能会释放各种有毒化合物，对患者健康构成潜在威胁。由于假牙在口腔中停留的时间很长，因此对修复材料的毒性进行详细检查和验证似乎至关重要。通过使用气相色谱等非常灵敏的测量技术，可以确定这些材料释放了哪些化合物。本文的目的是确定各种假牙清洁剂对用于假牙衬里的四种软质牙科材料释放有机化合物的影响。这些材料置于常用消毒剂（科瑞加片、次氯酸钠、洗必泰、过氧化氢）以及人工唾液中时，会产生13种化合物，如单体（甲基丙烯酸甲酯、甲基丙烯酸乙酯、甲基丙烯酸十二酯）、增塑剂（邻苯二甲酸二丁酯、邻苯二甲酸二乙酯、乙酰柠檬酸三丁酯）以及其他物质（如二苯甲酮）。对丙烯酸基材料和二氧化硅基材料释放的化合物进行比较表明，丙烯酸基材料对消毒剂的耐受性较差。
