Department of Geriatric Dentistry, Poznan University of Medical Sciences, Poznan, Poland.
Dent Mater. 2011 Mar;27(3):281-90. doi: 10.1016/j.dental.2010.11.003. Epub 2010 Dec 8.
The aim of this investigation was to determine the effect of storage in disinfectants and artificial saliva on a series of commercial soft lining materials for dentures. Changes in mechanical properties and the nature of chemicals released into these solutions were studied.
Four soft lining materials were studied (Vertex Soft® and Villacryl Soft®, both of which are plasticized acrylics; Molloplast B® and Mollosil®, both of which are silicone elastomers). All were cured according to manufacturers' instructions, and then cylindrical specimens (6 mm height × 10 mm diameter) prepared. These were stored under various conditions then loaded in uniaxial compression and the stress measured at a strain corresponding to a 10% deformation to determine Young's modulus. Storage involved exposure either to the following disinfectants: 2% aqueous chlorhexidine gluconate, 2% aqueous sodium hypochlorite, Corega Tabs® cleansing tablets or 3% aqueous hydrogen peroxide; or to artificial saliva. For the latter, storage involved either immersion in artificial saliva at 37°C for the whole study, or immersion for 16h a day and dry at room temperature for the next 8h each day. GC/MS was used to determine species leached into these solutions.
The acrylic materials Villacryl Soft and Vertex Soft became less elastic on storage for up to 28 days whereas the silicone materials Molloplast B and Mollosil, showed no change in elastic properties. Various compounds were found to be released from these materials, including EGDMA, methyl methacrylate and dibutyl phthalate. Generally, the silicones were more stable than acrylics, releasing smaller amounts of the various eluants. In all cases, amounts eluted were well below permitted exposure limits.
Practical denture cleansing agents affect the properties of soft lining materials, reducing their elastomeric character, acrylics being more adversely affected than the silicones. These changes are associated with the loss of various chemicals, including plasticizers and monomers, from the soft lining materials.
本研究旨在确定消毒剂和人工唾液对一系列商业义齿软衬材料的影响。研究了这些材料在储存过程中机械性能的变化以及向这些溶液中释放的化学物质的性质。
研究了四种软衬材料（Vertex Soft®和Villacryl Soft®，均为增塑丙烯酸酯；Molloplast B®和Mollosil®，均为硅橡胶弹性体）。所有材料均按制造商的说明进行固化，然后制备 6mm 高×10mm 直径的圆柱形试件。将这些试件在不同条件下储存，然后在单轴压缩下加载，并测量相应应变（10%变形）下的应力，以确定杨氏模量。储存条件包括暴露于以下消毒剂中：2%葡萄糖酸氯己定水溶液、2%次氯酸钠水溶液、Corega Tabs®清洁片或 3%过氧化氢水溶液；或暴露于人工唾液中。对于后者，储存条件包括在 37°C 的人工唾液中整个研究期间浸泡，或每天浸泡 16 小时，每天其余 8 小时在室温下干燥。GC/MS 用于确定浸出到这些溶液中的物种。
在储存长达 28 天期间，丙烯酸材料 Villacryl Soft 和 Vertex Soft 的弹性降低，而硅橡胶材料 Molloplast B 和 Mollosil 的弹性没有变化。从这些材料中发现了各种化合物，包括 EGDMA、甲基丙烯酸甲酯和邻苯二甲酸二丁酯。一般来说，硅橡胶比丙烯酸更稳定，释放的各种洗脱剂较少。在所有情况下，洗脱量均远低于允许的暴露限值。
实际的义齿清洁剂会影响软衬材料的性能，降低其弹性，其中丙烯酸材料比硅橡胶材料受到的影响更大。这些变化与软衬材料中各种化学物质（包括增塑剂和单体）的损失有关。
