Parker G D, Harnsberger H R
Department of Radiology, University of Utah Medical Center, Salt Lake City 84132.
Radiographics. 1991 May;11(3):383-99. doi: 10.1148/radiographics.11.3.1852933.
The radiologic and clinical records of 52 patients with radiologically documented perineural tumor were reviewed to assess the spectrum of tumors responsible, the nerves most commonly involved, and the optimal methods for imaging perineural tumor infiltration. Perineural tumor infiltration was most commonly seen with head and neck squamous cell carcinoma, followed by adenoid cystic carcinoma and several others, such as non-Hodgkin lymphoma, malignant schwannoma, minor salivary gland malignancy, and other sarcomas. The second and third divisions of the trigeminal nerve and the facial nerve were most commonly involved with perineural tumor. Both antegrade and retrograde perineural tumor spread were seen, although retrograde spread was significantly more common. Both high-resolution direct coronal computed tomography and magnetic resonance (MR) imaging clearly showed perineural tumor below the skull base. MR imaging best depicted skull base, cisternal, and brain stem perineural tumor infiltration. T1-weighted MR imaging before and after administration of gadopentetate dimeglumine is the study of choice in investigation of perineural tumor.
回顾了52例经放射学证实的神经周围肿瘤患者的放射学和临床记录，以评估相关肿瘤的谱系、最常受累的神经以及神经周围肿瘤浸润的最佳影像学检查方法。神经周围肿瘤浸润最常见于头颈部鳞状细胞癌，其次是腺样囊性癌和其他几种肿瘤，如非霍奇金淋巴瘤、恶性神经鞘瘤、小涎腺恶性肿瘤和其他肉瘤。三叉神经的第二和第三分支以及面神经最常受累于神经周围肿瘤。顺行和逆行性神经周围肿瘤扩散均可见，尽管逆行扩散更为常见。高分辨率直接冠状位计算机断层扫描和磁共振（MR）成像均清晰显示了颅底以下的神经周围肿瘤。MR成像能最佳地描绘颅底、脑池和脑干的神经周围肿瘤浸润情况。钆喷酸葡胺给药前后的T1加权MR成像是神经周围肿瘤研究的首选检查。
