Spaëth Dominique
Oncologie Médicale, Centre d'Oncologie de Gentilly, 2 rue Marie Marvingt, 54100 Nancy, France.
Expert Rev Anticancer Ther. 2008 Jun;8(6):875-85. doi: 10.1586/14737140.8.6.875.
Epoetin beta effectively increases hemoglobin levels, reduces the need for transfusions and improves the quality of life in patients with symptomatic chemotherapy-induced anemia with a range of solid tumors and lymphoid malignancies. Recent evidence-based guidelines recommend the once weekly administration of epoetin beta. This once-weekly regimen is generally well tolerated, and studies to date have reported that epoetin beta has a neutral effect on survival of patients with cancer. The once-weekly administration regimen is convenient for the physician and patient alike. Methods to further optimize this treatment are discussed.
β-促红细胞生成素能有效提高血红蛋白水平，减少输血需求，并改善患有一系列实体瘤和淋巴恶性肿瘤的有症状化疗所致贫血患者的生活质量。最近基于证据的指南推荐每周一次使用β-促红细胞生成素。这种每周一次的治疗方案通常耐受性良好，且迄今为止的研究报告称β-促红细胞生成素对癌症患者的生存具有中性影响。每周一次的给药方案对医生和患者而言都很方便。文中还讨论了进一步优化这种治疗的方法。
