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[使用具有特定性质的脱矿骨同种异体移植物填充颌骨缺损]

[The use of demineralized bone allograft with given properties for filling in jaw defects].

作者信息

Lomnitskiĭ I Ia, Li L N

出版信息

Stomatologiia (Mosk). 1991 Mar-Apr(2):54-7.

PMID:1853386
Abstract

The course of reparative regeneration was studied in 112 rabbits 3-4 kg b. w., in whom perforating defects 10 mm in diameter were filled with ground allobone and mineral-free allobone preserved in 0.25 percent formalin or mineral-free allobone impregnated with antiseptic solution. Histologic, histochemical, and morphometric investigations have revealed that the latter variant of defect filling lead to the most active graft restructuring with development of lamellar bone tissue. No cartilagenous stage was recorded over the course of bone tissue development in any case. Preservation of mineral-free bone in 0.25 percent formalin solution reduced its osteogenic abilities.

摘要

在112只体重3 - 4千克的兔子身上研究了修复性再生过程,这些兔子的直径为10毫米的穿孔性缺损用磨碎的同种异体骨以及保存在0.25%福尔马林中的无矿物质同种异体骨或用抗菌溶液浸渍的无矿物质同种异体骨填充。组织学、组织化学和形态计量学研究表明,后一种缺损填充变体导致移植物最活跃的重塑,并形成板层骨组织。在任何情况下,在骨组织发育过程中均未记录到软骨阶段。将无矿物质骨保存在0.25%福尔马林溶液中会降低其成骨能力。

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