Moeller Sebastian, Freiwald Winrich A, Tsao Doris Y
Institute for Brain Research and Center for Advanced Imaging, University of Bremen, Post Office Box 330440, D-28334 Bremen, Germany.
Science. 2008 Jun 6;320(5881):1355-9. doi: 10.1126/science.1157436.
The brain processes objects through a series of regions along the ventral visual pathway, but the circuitry subserving the analysis of specific complex forms remains unknown. One complex form category, faces, selectively activates six patches of cortex in the macaque ventral pathway. To identify the connectivity of these face patches, we used electrical microstimulation combined with simultaneous functional magnetic resonance imaging. Stimulation of each of four targeted face patches produced strong activation, specifically within a subset of the other face patches. Stimulation outside the face patches produced an activation pattern that spared the face patches. These results suggest that the face patches form a strongly and specifically interconnected hierarchical network.
大脑通过腹侧视觉通路沿线的一系列区域处理物体，但负责分析特定复杂形式的神经回路仍然未知。一种复杂形式类别，即面孔，在猕猴腹侧通路中选择性地激活六个皮质区域。为了确定这些面孔区域的连接性，我们将电微刺激与同步功能磁共振成像相结合。对四个目标面孔区域中的每一个进行刺激都会产生强烈的激活，特别是在其他面孔区域的一个子集中。在面孔区域之外进行刺激会产生一种使面孔区域不受影响的激活模式。这些结果表明，面孔区域形成了一个紧密且特定互连的层次网络。
